HIV /AIDS LIFE EXPECTANCY : FACTORS GOVERNING LIFE OF AIDS PATIENTS

PROF.DRRAM ,HIV/AIDS,SEX DISEASES,SEX WEAKNESS & ABORTION SPECIALIST
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Factors that influence life expectancy are generally considered either static (or fixed) or dynamic (able to change or fluctuate over a short period of time).

Static factors, like race or sexual orientation, influence life expectancy not so much because a person is either white or African American,African,Indian or from any where or identifies as gay or heterosexual. Rather, longevity is associated with a multitude of risk factors within these specific population groups.

For instance, high levels of poverty in African American communities (24.9%),African indian poor patients and the consequential lack of access to healthcare negatively impacts the survival rate when compared to white population. Conversely, stigma reduction and access to community-specific HIV care may be contribute to the higher survival rates among men who have sex with men (MSM).

Dynamic factors, on the hand, generally have very strong causal effects insofar as survival time is concerned. Some of these, like treatment adherence, relate specifically to the preservation or deterioration of a person's immune function. Others, like smoking, contribute to the premature development of non-HIV-related comorbidities, such lung cancer. Still others, like injection drug use, are affected both fronts—both behavioral vulnerability and a person's vulnerability to infection.

CD4 count at the time of cART initiation remains one of the strongest indicators of life expectancy. Starting therapy at a CD4 count below 350 cells/ µL correlates to a quantitative reduction in life-years. Simply put, as the CD4 continues to dip beneath the 350 threshold, so, too, does life expectancy—by as much as 22 years, according to an analysis of the NA-ACCORD study data.

HIV-infected smokers lose more life-years to smoking than to HIV, say researchers from Department of Infectious Diseases at the University at Copenhagen. In fact, the risk of death from smoking is twice as high among smokers with HIV than those without. When compared to non-smoking people with HIV, smokers with HIV trim as much as 12 years from their lives, reducing life expectancy to just under 63 years.

Race and HIV longevity are integrally linked. Quite simply, HIV-positive non-whites live, on average, 8.5 year less than their white counterparts. That's a 15% difference, with the lowest life expectancy seen among African-Americans.

Injection drug users (IDUs) suffer from substantially increased mortality, both in terms of HIV-related infections and non-HIV-related comorbidities (like liver cancer). According to a collaborative cohort study of 6,269 IDUs in North America and Europe, the strongest contributing factors to lower life expectancy rates were treatment adherence and hepatitis C (HCV) co-infections. All told, life expectancy for IDUs is 20 (or more) years less than all other HIV groups.
Meanwhile, most research indicates that gender has no impact whatsoever on either disease progression or mortality. Moreover, white MSM are seen to have among the longest life expectancy of all HIV groups.
IN BRIEF IF TREATMENT STARTED SOON NOT BELOW 350 AS IN INDIA WITH GOOD ARV DRUGS HAVING LESS SIDE EFFECTS NOT AS IN INDIA ART CENTRES WHERE ONLY STAVUDINE NOT GIVEN BUT ZIDUVUDINE AND LAMOVUDINE AND NEVIRAPINE STILL USED EVEN PROTEASE INHIBITOR LIKE RALETAGIVIR, ATZANIVIR, INDIVINAVIR,LACKING MODERN INHIBITOR AND RECEPTOR BLOCKERS NOT USED BUT STILL REGUAR TREATMENT,GOOD ADHERANCE,A GOOD LIFE STYLE WITHOUT ADDICTION OF MULTIPLE SEX PARTNERS,DEVOID OF ALCOHOL,DRUGS AND CIGARETTE WITH GOOD DIET,NUTRITION AND TAKING PREVENTION FROM UNNECSSARY COLD HEAT,TRAUMA,PERSONAL FOOD AND WATER HYGEINE ALL LEADS TO GOOD SURVIVAL .PREVENTING IMMUNISATION WITH PREVENTIVE PROPHYLAXIS OF SOME INVECTION LIKE PNEUMONIA,DIARRHOEA,TOXOPLASMA ETC AND ERALY CHECK UP FOR OPPUTUNISTIC INFECTIONS ETC ALL LEADS TO GOOD SURVIVAL.
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