Abstract
The social impact of bone and cartilage pathologies entails high costs in terms of therapeutic treatments and loss of income. For these reasons,
the trend in research is now moving towards preventive interventions and therapeutic solutions that can lead to an enhancement of tissue
regeneration and the reduction of degenerative mechanisms. Orthopaedic surgeons have always sought means to use biological solutions to
promote healing and regeneration and this need is most evident in young athletes with knee injuries requiring repair of the existing tissues,
who are not candidates for joint replacement.

Keywords
Cartilage, bio-orthopaedics, stem cells, platelet-rich plasma