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Feb16
HIV /AIDS VIRAL LOAD AND HIV TRANSMISSION RISK
HIV /AIDS VIRAL LOAD AND HIV TRANSMISSION RISK

PROF.DRRAM ,HIV/AIDS,SEX DISEASES,SEX WEAKNESS & ABORTION SPECIALIST
profdrram@gmail.com,+917838059592,+919832025033 DELHI –NCR,INDIA
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HIV /AIDS IS CONTROLLED BY GOOD ARV OR ANTI RETROVIRAL MEDICINES AND AS WE START TTAKING MEDICINES REGULARLY WE FIND THAT OUR HIV QUANTITY IN OUR BODY IS DIMINISHED OR OUR VIRAL LOAD BECOMES LESS AND IT IS BELOW 50COPIES/ML OF BLOOD WE ASSUME THAT OUR VIRUS IN BODY IS VERY LESS AND NOW EVEN IF WE MEET OUR SEX PARTNER WITHOUT CONDOM RISK OF TRANSMISSION TO HIV NEGATIVE PARTNER IS MINIMAL BUT RISK BY BLOOD MIXING IS STILL IN GOOD PERCENTAGE.SO FOR HAVING CHILDREN SEX MAY BE ALLOWED ONCE OR TWICE WITHOUT CONDOM IN SERODISCORDANT (ONEPOSITIVE ANOTHER NEGATIVE) OR BOTH POSITIVES IF BOTH HAVE MINIMAL VIRAL LOAD BUT NOT MUCH SEX WITHOUT CONDOM ALLOWED AS IN BOTH POSITIVE TWO VARIETY OF HIV VIRUS OR GENOYPE MIX AND MAY CAUSE IT RESISTANT TO DRUG IN ONE PARTNER.
HOW MUCH TRUE IS ABOVE STATEMENT IS DEFINED BY STUDY DONE BELOW.
A January 2008 statement by the Swiss Federal AIDS Commission sparked considerable controversy, suggesting that HIV positive individuals on antiretroviral therapy who are fully adherent, maintain an undetectable viral load (below 40 copies/mL) for at least six months, and have no concurrent sexually transmitted infections are "not sexually infectious" (at least via heterosexual vaginal intercourse).

At the Mexico City conference, commission president Pietro Vernazza maintained that under the specific circumstances described, unprotected sex with a person with undetectable viral load carried a risk similar to that of sex using a condom: not 100% safe, but within a "comfortable range." But the risk is not non-existent, given that people on effective therapy may experience occasional transient viral load increases, or "blips," and that HIV may be present in genital and anal secretions even if it is undetectable in the blood.

As described in the July 26, 2008, issue of The Lancet, Australian researchers used a mathematical model to quantify the small transmission risk under the circumstances described in the Swiss statement. Assuming that each couple engaged in 100 sexual acts per year, they calculated the cumulative annual probability of transmission as .22% for female-to-male transmission, .43% for male-to-female transmission, and 4.3% for male-to-male transmission. In a population of 10,000 serodiscordant couples, this would translate to 215 expected instances of female-to-male transmission, 425 instance of male-to-female transmission, and 3,524 instances of male-to-male transmissionabout four times greater than the risk when using condoms.

"Although we agree that effective antiretroviral treatment which leads to undetectable viral load is likely to have a substantial effect on reducing infectiousness," the researchers concluded, "our analyses suggest that it should not replace condoms."


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