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Feb07

IS HIV UNDETECTABLE IS HIV NEGATIVE / HIV CURED FOR PATIENTS

PROF.DRRAM ,HIV/AIDS,SEX Diseases, Weakness & Hepatitis Expert 
profdrram@gmail.com,+917838059592,+919832025033,DELHI,INDIA
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HIV /AIDS is now effectively controlled by good medication of HAART OR HIGHLY ACTIVE ART IF MEDICINES ARE TAKEN REGULARLY AND PT IS NOT EXPOSED TO DRUGS/ALCOHOL OR MULTIPLE SEX AND ADOPT GOOD NUTRITION FOOD EXCERCISE AND REGULAR MEDICATION.
AFTER A LONG TIME IT IS SEEN HIV VIRUS IS NO MORE DETECTABLE IN THESE PATIENTS AND THESE ARE DECLARED HIV NEGATIVE BUT IF TREATMENT IS STOPPED FOR FEW MONTHS IN SOME PATIENTS EVEN IN CHILDREN WHOSE MOTHER WAS HIV POSITIVE AND HIV MEDICATION STARTED SOON AFTER BIRTH EVEN IN THESE PATIENTS HIV HAS RECURRED IF TREATMENT IS STOPPED AFTER THEY REMAIN NEGATIVE FOR A LONG TIME SO A COMPLETE ERADICATION OF HIV IS NOT POSSIBLE SO LIFE LONG HIV TREATMENT IS ADVISED AS HIV VIRUS SINCE INFECTION BINDS WITH GENOME OF CD4 CELLS AND REMAIN HIDDEN IN SOME LYMPHNODES OR BONE MARROW IN SMALL AMOUNT NOT IN BLOOD SO THEY ARE NOT DETECTABLE IN BLOOD BUT THEY RECURE FROM SUCH HIDDEN PLACE.
So From a transmission point of view, having an undetectable viral load is close to being negative. And from the standpoint of prognosis and life expectancy, people with undetectable viral loads and normal CD4 counts have more in common with HIV-negative people than they have with people with untreated HIV infection they live almost a normal quality and quantity of life but with certain mandatory drug intake and a good life.

But there are still important differences between someone with well controlled HIV and someone without HIV -- if there weren't, we wouldn't still be looking for a cure. Even with well controlled HIV, you have a chronic medical condition that is expensive to treat and that causes an increase in chronic inflammation and immune activation. You still have viral DNA integrated into your own genome. So it is not good to say that "undetectable is the new negative,".
There is a growing number of patients who have encountered with hiv persons by sex or blood contamination or mother to child hiv is still undetectable in their blood but symptoms appear like of hiv or other sex diseases as we know window period of hiv is long so SUCH NEGATIVE SHOUL BE CALLED A NEGATIVE IS ALSO CONTROVERSIAL EVEN TESTED NEGATIVE BY CARD OR ELISA TEST NEGATIVE FOR 3- OR MORE MONTHS .MODERN DAY AFTER 06 MONTHS IF NO HIV WE CALL THEM NEGATIVE BUT SYMPTOMS NUCLEIC ACID TEST AND THESE MUST BE FOLLOWED FOR 18-24 MONTHS.



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