RECREATIONAL DRUGS AND SEX RELATED TO MORE HIV & STDs

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Recreational drug use can increase the risk of Stds and HIV infection as it is often with alcohol or sedating or exciting pills no protection like condom is used under influence of such drug,anal oral,vaginal sex done in violant manner and it is forceful and ofter painful torture sex done by burning with buts of cigarette,cutting parts skin ,tearing mucosa for bleeding and cry done for pleasure . Also, for people taking antiretroviral medications (ARVs) to fight HIV, there can be some serious interactions between drugs and ARVs. These interactions can lead to under- or overdoses of ARVs or recreational drugs.If recreational drugs are injected using shared needles, there is increased risk of infection with blood-borne diseases, including HIV and viral hepatitis.Drug users should be tested regularly for STDs and HIV.The long-term symptoms of persistent drug use may be similar to those of HIV or AIDS. Be sure to tell your medical provider about any of the recreational drugs you use.
We do know that heavy drug use may negatively impact a person's sleep schedule, appetite and overall health. Drug use can cause the immune system to weaken and exacerbate the side effects of ARVs. In turn, this can provide a pathway for opportunistic infections to develop.Another risk of drug use is missing ARV doses and poor adherence. This can lead to HIV resistance.
Drug Interactions:Recreational drugs will likely interact or interfere with ARV therapy, increasing or decreasing ARV drug levels. This can lead to ARV treatment failure. Also, drug interactions can cause a serious, possibly fatal increase in the level of recreational drugs.There is little research on the effects of interactions between ARVs and recreational drugs on the human body. This is because the use of recreational drugs is illegal and they cannot be provided to people with HIV, even to study the effects.
The liver metabolizes most ARVs and all protease inhibitors. Recreational drugs metabolized in the liver can cause serious drug interactions.
Alcohol :Excessive alcohol use may weaken the immune system function and threatens the long-term benefits of ARV therapy. Alcohol can increase blood levels of abacavir.Chronic alcohol use affects treatment adherence by interfering with a person's ability to stick to a regular ARV regimen. Alcohol use may increase the risk of pancreatitis when used with didanosine .
Cocaine:Although interactions between cocaine and ARVs are unlikely to increase cocaine toxicity, the cocaine use may decrease ARV effectiveness by diminishing adherence.
Crystal Meth, Methamphetamine, Crank, Glass, Tina, Others:A recent study found that gay men who use crystal meth have five times the risk of HIV infection as non-users. Serious and dangerous drug interactions are highly likely. When methamphetamine is used with ritonavir (Norvir), including when used for boosting other ARVs, amphetamine levels can double or triple.
Ecstasy/MDMA:Ecstasy uses the same liver pathway as protease inhibitors. This can cause very high levels of ecstasy in the body of people taking protease inhibitors. There is one documented case report of a death due to an interaction between ecstasy and ritonavir. Ecstasy can also increase the risk of kidney stones when used with indinavir (Crixivan) due to dehydration.
GHB (Xyrem, "Date Rape Drug"):This drug is primarily metabolized by the liver. There are no known interactions between GHB and ARVs. Protease inhibitors may increase GHB levels. Protease inhibitors may increase GHB levels.
Ketamine (K, Special K):This drug is primarily metabolized by the liver. All protease inhibitors may cause high levels of ketamine. This could cause hepatitis. To date, there are no case reports or studies of interactions between ketamine and ARVs.
LSD:The metabolism of LSD is not understood. Interactions with ARVs are possible but unknown.
Marijuana:There are no known interactions between marijuana and ARVs. Interactions may be greater if marijuana is eaten rather than smoked. Use with protease inhibitors may increase effect of marijuana.