As we are progressing studies show that dogs can detect volatile organic compounds in the urine of men with prostate cancer. One such study showed that the animals could sniff out prostate cancer with 98 percent accuracy.Scientist have identified the molecules that likely give the urine of men with prostate cancer its unique scent, and they have developed a chemical sniff test to detect them.

   Now, Prof. Mangilal Agarwal, and his colleagues - including Dr. Amanda Siegel, an associate director of research and development at Indiana University-Purdue University Indianapolis, has been developing a sensor to detect hypoglycemia (low blood sugar) in human breath and now reserching out chemical substance in Urine of prostatic cancer patients which can be sniffed by Human like dog .For their study, the team tested urine samples collected from 100 men who were undergoing prostate biopsies.The researchers noted that some previous studies had experienced problems with chemical degradation.Thus, to better preserve the samples during analysis, they added sodium chloride and neutralized their pH.

Using gas chromatography-mass spectrometry to analyze the volatile organic compounds in the air above the urine samples, the team found a set of small molecules that appear to be unique to prostate cancer.The molecules were present in 90 percent of samples from men who were subsequently found to have prostate cancer, but they were not present in samples from men who did not have it.

The researchers are already planning to validate their findings with a large-scale study involving several health centers. They also hope to compare their findings with results obtained from dogs, with the help of a local dog trainer.

After skin cancer, prostate cancer is the most common cancer in men in the United States, where around 1 out of every 7 men can expect to be diagnosed with the disease during their lifetime.There are currently more than 2.9 million prostate cancer survivors living in the U.S over the age of 60yrs.

While early detection is one of the most important factors in helping men to survive prostate cancer, diagnosis is not straightforward. It usually relies on a combination of a digital rectal exam and a blood test to measure prostate-specific antigen (PSA) to help decide whether a biopsy should be done.

However, biopsies are expensive, uncomfortable, and carry the risk of infection. Unfortunately, thousands of men undergo the procedure - which involves inserting a needle into the prostate gland to remove pieces of tissue for analysis - only to discover that they do not require cancer treatment.One of the causes of unnecessary biopsies for prostate cancer diagnosis is that other conditions - such as a prostate infection - can also give high PSA levels. Consequently, the PSA test is widely recognized as unreliable, and so biopsies are performed in order to get a clearer answer.Scientists are therefore investigating various alternative ways to improve prostate cancer diagnosis without having to rely on biopsies.