HIV / AIDS CONTROL : FEW NEW STUDIES IN MICE TO PRODUCE BETTER DRUGS FOR CONTROL OF HIV / AIDSWORLD WIDE TO CONTROL HIV/ AIDS IN FUTURE 

PROF.DRRAM ,HIV/AIDS,SEX DISEASES,SEX WEAKNESS & ABORTION SPECIALIST 
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1.CHINESE RESEARCH OF VIRAL VIF PROTEIN;--
Chinese researchers have claimed to have made a significant breakthrough in the study of HIV virus, offering hope of developing new medications to treat or even cure the disease.The researchers said they have made the breakthrough in the structural analysis of the viral infectivity factor (Vif) of the HIV virus, which will help in the development of new medications to treat or even cure the disease.

The new research, published on the website of science journal ‘Nature’, was carried out by a team of Chinese researchers led by Huang Zhiwei, professor of structural molecular biology with the School of Life Science and Technology at Harbin Institute of Technology, China.The research reveals the structural analysis of HIV-1 protein Vif, whose role is to subvert antiviral activity.The results lay a foundation for the design of novel anti-HIV drugs, the paper said.Ever since the AIDS virus was discovered in 1981, people have had insufficient knowledge of the virus itself, including the structure of Vif, which is extremely important to virus infection and replication, the lead researcher said.Analysing Vif structure is vital to the design of AIDS treatment medicines. The study of Vif structure has been the most important subject for scientists worldwide on AIDS in recent years.China is the first to come out with research achievements on the subject..He said the research team has begun cooperation with drug producers to develop new types of medicines for treating AIDS.

‘After medicine development succeeds, it will break a new path for treating AIDS worldwide, even hopefully curing it,’ Huang said, adding that it will also pave the way for Chinese-made drugs to fight HIV/AIDS. China has got 434,000 people living with HIV/AIDS, according to government statistics. Worldwide, the number reached about 35 million at the end of 2012.

USA TEAM TO PRODUCE A POISON TO KILL VIRUS:A team of researchers has demonstrated in a mouse model that an HIV-specific poison can kill cells in which the virus is actively reproducing despite antiretroviral therapy.According to the researchers from University of North Carolina and NIH, such a targeted poison could complement antiretroviral therapy, which dramatically reduces the replication of HIV in infected cells but does not eliminate them.

The 40 mice in the experiment were bioengineered to have a human immune system. They were infected with HIV for several months and then given a combination of antiretroviral drugs for four weeks.Half of the animals subsequently received a two-week dose of a genetically designed, HIV-specific poison, or immunotoxin, to complement the antiretrovirals, while the other half continued receiving antiretrovirals alone.The scientists found that, compared to antiretrovirals alone, the addition of the immunotoxin significantly reduced both the number of HIV-infected cells producing the virus in multiple organs and the level of HIV in the blood. 

ENZYME DEVELOPED TO CUT VIRUS FROM INFECTED CELL;---
The process, developed by biomedical researchers at Dresden Technical University involves using an enzyme to 'cut' the virus from the DNA of infected cells, leaving them alive and well. 

The treatment has, so far, only been shown to work in HIV-infected mice. Clinical trials would be needed to establish whether it could work in people. As it stands, there are no plans in place to fund a trial.The treatment would work by taking blood from infected patients, treating it with the enzyme, and transfusing it back into the patients. The enzyme targets stem cells, altering their DNA. Once reintroduced into the body, these cells would reproduce, and cut the HIV from other infected cells.

Such results were seen in the mice. Professor Hauber said that 'the amount of virus was clearly reduced, and even no longer to be found in the blood.'