Rheumatoid Arthritis Therapy
Posted by on Wednesday, 20th May 2009
Amavata (Rheumatism)
Introduction
The term “Ama” means unripe, immature and undigested. It is resulted as a consequence of impaired functioning of ‘kayagni’. According to vagbhata; due to the hypo functioning of ushma (Agni), the anna-rasa undergoes fermentation and or putrification (dushta). It is this state of Rasa, which is known as ‘Ama’. The vitiated doshas along with Ama causes Amavata.
Hetu-Etiological Factors
Indulgence in incompatible foods and habits.
Excess of physical activity immediately after taking fatty foods.
Those with poor digestive capacity.
Use of food and drink, which are heavy to digest.
Use of food, which is rough, cold, dry, unclean, antagonistic in nature.
Emotional factors such as passion, anger, greed, confusion, envy; grief, excitement, fear etc.
Is responsible for Amavata.
Signs and symptoms of Amavata
cardinal symptoms of amavata are
(Vriscik damsha vata vedana)Morning pain severe in nature
(Sanchari Vedana)shifting pain
(Stambha) stiffness of joints
(Jwara )Increase temperature
(Karmahani) loss of movements
(Sandhi Vikruti) joint deformity.
(Kshudhamandya) Loss of appetite
Signs and Symptoms of Amavata according to doshik dominance
Vitiated Vata produces colicky pain, body ache, abdominal distension, giddiness, stiffness of back and waist, constriction and spasm of blood vessels.
Vitiated Pitta produces fever, diarrhea, thirst, giddiness and delirium.
Vitiated Kapha produces vomiting, anorexia, indigestion, fevers with cold, lassitude and heaviness in body.
Classification
Vataj - Where vata is predominant (pain is severe in this type).
Pittanubandhi - Where pitta is predominant (burning sensation and redness of the affected joints is present).
Kaphanubandhi - Where kapha is predominant (loss of movement and itching is seen in this type).
Sadhyasadhyata - Prognosis
Disease with early onset and single dosha prominence in young individual can be cured with proper treatment and with religiously following the do's and don'ts.
As the disease become chronic it involves multiple systems, which makes the disease uncurable. If it is present with signs of complications then it may produce serious threats to life.
Chikitsa - treatment
Line of treatment:
Shodhan-:
Snehpana (Ingestion of unctuous substances -: various oils specially prepared with Rasna, Dashmoola, Nirgundi are used for this purpose. Especially castor oil is considered as the best oil to be used in the treatment of amavata.
Langhana (fasting )-: it is done by means of complete absence of food, or by giving preparations of Mudga Yusha, laja Manda, Peya(rice water soup), kulith(horse gram) and Yava (barly).
Swedana (fomentation) is very useful mode of treatment in amavata. Specially complete dry sweda in the form of Ruksha kuti sweda (sauna bath), Dry fomentation-using sands like dry substances, Upanaha (local application) of non-unctuous substances are very effective in relieving the pain.
Virechan (Purgatives)-: Virechan with castor oil is very useful in treating amavata.
Basti (medicated enema) various medicated enemas
like Vaitaran Basti, Dashmoola Kwath Basti, Kshar Basti, Erandmoola Yapan Basti are useful in relieving the pain in amavata
Shaman Chikitsa -: commonly used drugs
Decoctions
Rasna-panchak kwatha.
Rasna saptak kwatha
Panchakol kwatha.
Dashmool kwatha with eranda taila.
Churna-:
Ajamodadya choorna
Panchakol choorna with lukewarm water
Shunthi choorna
Almabushadya choorna
Vaishwanar choorna
Vati / Guggulu
Simhanad guggulu
Brihat yogaraj guggulu
Ghrita
panchakola ghrita
rasnadi ghrita
Taila
Eranda taila
Saindhavadya taila
Lepa
Shunthi lepa
Bachang-tentu lepa
Rasaushadhi
Amavatari rasa
Rasraj ras
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HOW TO GET RID FROM DIABETES
Posted by on Wednesday, 20th May 2009
Diabetes- what it means to you ?
Everyone has glucose in their blood, whether or not they have diabetes. This glucose comes from food. When we eat, the digestive process breaks down food into glucose, which is absorbed into the blood in the small intestine. People who don't have diabetes rely on insulin, a hormone made in the pancreas, to move glucose from the blood into the body's billions of cells. But people who have diabetes either don't produce insulin or can't efficiently use the insulin they produce. Without insulin, they can't move glucose into their cells.
Glucose accumulates in the blood -- a condition called hyperglycemia ("hyper" = too much, "glycemia" = glucose in the blood) -- and over time, can cause very serious health problem. Although there are various types of diabetes but everyone with diabetes has one thing in common that they have little or no or reduced ability to move glucose/sugar from the blood stream into the cells which is essential because glucose is body's primary fuel
Types of Diabetes :
Idiopathic diabetes mellitus --- IDDM
NIDDM----Secondary diabetes
Gestational diabetes
Symptoms :
Cases of mild to moderate Diabetes are usually diagnosed on a routine health check-up or during pre operative investigations done for fitness for surgical procedures. Patients may go to a physician for some chronic non-healing problem like itching, cough, or a non-healing wound. The patient may be asked for a routine sugar check-up and is diagnosed as a case of diabetes. The classical symptoms of diabetes may not be essentially present. At times diabetes may be suspected by observing the following symptoms:
When one looks for the symptoms of diabetes the common symptoms found are
For Type 1:
Excessive urination
Excessive thirst
Excessive hunger
Episodes of extreme weakness or even fainting
Type 2:
The need to urinate more than usual
Excessive thirst
Unusual weight loss
Feeling of being un-well/weak or tired
Blurred vision
Tingling or numbness in hands or feet
Frequent and recurring infections such as urinary tract infections, boils, and fungal infections
Difficulty with erections in men, and unusual vaginal dryness in women
Causes Of Diabetes :
An elaborate description of the causative factors of diabetes is done in the Ayurvedic texts. More stress has
been laid on sedentary habits, lack of exercise and the consumption of diets having high calorie value The
causative factors from Ahara (diet) includes the use of new grains (of recent time) of less than one year, use of
new peas, the use of sugar-cane juice, frequent use of milk and milk products, fresh wine, curd preparations,
meat soups of different animals residing near or in water. These causative factors are responsible for the
increase of the humor Kapha (Kapha dosha). Vihara (Behavioral patterns) includes excessive sleep during day
and night, lack of exercise, laziness etc. Even worry, grief, anger and anxiety are said to be among the
causative factors of Prameha in susceptible individuals.
Modern Views
According to the modern science though the exact cause of diabetes is not known but there are some
predisposing/risk factors which increase the chances of occurrence of the disease. These can be listed as:
Age: Increasing age.
Genetic or heredity factor: diabetes is one of the known diseases that runs in families.
Viral infections affecting especially the pancreas.
Poor diet (Malnutrition related diabetes).
Excessive and long-term consumption of sweet products (like Milk products) as per Ayurveda.
Being overweight or obese.
Leading a sedentary lifestyle. Lack of exercise, especially in those who are overweight, increases risk.
Stress.
Drug induced.
Modern management of diabetes:
The principles of management of diabetes in the modern medicine are basically to achieve an optimum control
of blood sugar levels. The measures that are commonly employed are three fold and can be listed below:
Diet control
Exercise
Drug management
Patient Education
1) The role of Diet in Diabetes:
Whatever diet may be prescribed or recommended for a patient of diabetes the common principles to follow are:
Reduction of weight.
Eating fewer sugary or fatty foods.
Reducing blood pressure.
Do not skip a meal.
Do not eat too often of outside food (Fast food etc) .
2) Exercise in therapy of diabetes:
In NIDDM patients, regular exercise forms an important component of therapy along with dietary regulation
and oral hypoglycemic agents. Appropriate monitoring should be done to avoid complications. Exercise should
not be recommended in all IDDM patients but efforts should be made to make it possible for those who want to
exercise to be able to do so as safely as possible.
General Principles for exercise in Diabetics:
To be effective exercise must be performed regularly. Choose an exercise that one enjoys and which suits the
needs of individual patients. Daily exercise is preferable, however for the desired metabolic effect it should be
undertaken for at least 3-5 days per week. The duration should be 15-60 minutes. The ideal time is on an
empty stomach in the morning or evening. Any exercise should have a warming up and cooling down period of
5-10 minutes. Most diabetics may need to reduce the dose of insulin and oral drugs when they exercise
regularly.
The best exercise recommended to a diabetic stepwise increasing exercise plan of aerobic exercise. Plain brisk
walking is the simplest and safest of all excises. It can be started by anyone. Aerobic (isotonic) exercises like
walking, running cycling, jogging, swimming, skipping and games like badminton, tennis and basketball
stimulate the cardio respiratory system and increase the utilization of glucose to a great extent. Isometric
exercises like weight lifting, sustained handgrip must be avoided in diabetics as they increase the arterial
pressure.
The Ayurvedic mode of management of Diabetes
Since thousands of years the ancient physicians of this great nation have been successfully treating Prameha
with the Ayurvedic measures and drugs. Many drugs have already been screened for the their anti-diabetic
property/blood sugar lowering property. The importance of diet and exercise is also stressed in Ayurveda. The
Ayurvedic diet regimens and the recipes may serve as a good replacement for the Diabetic patient. Though
many of the diabetic drugs that are used today have a good sugar lowering (Hypoglycemic property they
essentially act at the basic pathology. This helps in controlling the diabetes and not only the blood sugar. The
management modalities can be categorized as:
Vyaayam (Exercise),
Pathya (dietary regulation),
Panchakarma (Bio-purification procedures) and
The use of therapeutic measures (Medicines).
The herbal drugs used in the management of Prameha are bitter, astringent and pungent in taste.
Individual herbs that are extensively used in the management of diabetes:
1. Eugenia jambolana:(Jamun beej churna) Dry seed powder of Jamun fruits have to be used in a dose of one-
teaspoon twice/thrice daily with lukewarm water.
2. Gymnema sylvestre: (Gudmar patra churna) Dry leaves of this plant have to be used one teaspoon daily with
lukewarm water. The leaves when chewed render the mouth tasteless to sweet for 45 min to one hour.
3. Pterocarpus marsupium (Vijaysar kashtha churna) Bark of this plant is available in the form of powder.
Cubicals or Vijaysaar glasses are also very popular. The piece of Vijaysaar is kept in water overnight or water
is kept in the glass is consumed early morning on empty stomach. One should discard these cubicals or glasses
once there is no colour change observed in water.
4.Ficus bengalensis (Nyagrodha twaka churna) This is banyan tree bark. A decoction of bark is to be prepared
and consumed twice daily in a dose of 40 to 80ml. The decoction is prepared by taking around 25-50gms of bark
to which 4 cups of water are to be added. It is heated to make one cup, which has to be consumed.
5. Shilajeet Popularly known as Rock salt, various reputed companies have Granular or powdered form of
Shilajeet available. Though not very useful in reducing the blood sugar it is an excellent remedy to for loss of
libido in males and in case of generalized weakness.
6. C. Tamal (Tejpatra) This is very commonly used as a spice in preparing food products. A diabetic patient
may make a point to add the leaves of this plant in his food. Also the powder of leaves may be consumed.
7. Fenugreek seeds (Methi churna) Seeds of Methi have to be soaked in warm water overnight and chewed
early in the morning with warm water. One may take powder of these seeds with warm water twice daily.
Methi powder may be added to the wheat flour to prepare chapattis.
8. Momordica chirantia Karvellaka (Karella) Juice of Karela should be taken early in the morning in a
quantity of 20 ml. The dried whole fruit powder can also be consumed in the dose of ½ to 1 teaspoon twice
daily.
9. Embelica officinalis (Amala) When fresh Amla are available one may take Amla juice 20 ml daily or
otherwise powder of Amla fruits may be taken twice daily.
10. Curcuma longa (Haridra) Haldi powder along with Amla juice is a very good combination in patients of
Diabetes. It is especially useful in prevention as well as treatment of patients of Diabetic eye disease. Haldi can
be put in milk as well.
11. Kirat tikata (Chirayata) A decoction of this plant is to be taken daily early morning. It is a very popular
remedy used in all parts of the country for various skin disorders and hence forms a perfect remedy for skin
infections in Diabetics .
An ayurvedic physician may advice some good Ayurvedic drugs even in patients who do not respond
to the oral hypoglycemic drugs or even insulin. These are then termed as adjuvant ayurvedic drugs. Not only
do these help in lowering the blood sugar but also prevent the long-term complications of diabetes. We shall
name some of these combinations/preparations:
Chandraprabha vati: In a dose of 500 mg twice or thrice daily. This is specially used in patients having
Diabetes with Urinary tract infection or in females having leucorrhoea. This can be used along with
Gorshuradi guggul in the same dose.
Trivang Bhasma: This is a combination of three bhasmas namely Naga, Vanga and Yashaha Bhasma. It is to be
taken in a dose of 125mg twice daily available in the form of powder. It is very useful in conditions where there
is excessive urination, Male sexual problems as well as to treat generalized weakness.
Dhatri Nisha: A combination of Haldi powder and Amla Rasa and has to be taken early morning and is
especially useful in Diabetic eye condition.
Vasant kusumakar rasa: A very useful tonic for diabetics especially useful in the stage of complications it has
to be consumed in a dose of 125 mg twice daily. Along with having a general tonic effect it also helps in
Diabetic eye condition and in preventing various conditions developing due to Nerve weakness.
Many of the well-known pharmaceutical companies have also come up with good Anti diabetic herbal
combinations. These preparations have been extensively clinically and scientifically studied at various centers
and have proven their efficacy. They are easy to administer and their dose may be well regulated. These
preparations have to be preferably consumed as per the advice of the physician. The well-known combinations
available today include :
Hyponidd (Charak Pharma)
Diabecon (Himalaya Drugs Co)
Asanad (Arka Shala)
Cogent Db
Glucomap (Map)
Karnim (Universal Medikit)
Debix (Sandu Brothers)
Ilogen Excel (Pankaj Kasturi)
Madhunshini Vati ( Patanjali Pharmacy)
Other associated conditions with diabetes and its management:
Diabetes is a long lasting and a chronic disease. A patient of diabetic may suffer from some very distressing
symptoms so much so that he even forgets of his diabetic in agony of this complain. A physician has to look for
the safe management of these symptoms that shall not affect the diabetic status as well as not have a long-term
complication.
We shall discuss some of these complaints and try to see how they can be managed.
1) Diabetes with Arthritis: Yograj guggul, freshly prepared decoction of Dasamoola, Rasna saptak, a paste
of sunthi or Dasang lepa may be applied on the affected joint.
2) Diabetes with constipation: Powders like Gandharva haritaki, Isabgool, Panchaskar, Hingvastak can be
used to relieve constipation.
3) Diabetes with burning sensation in the soles and palms: this can be well managed with Mangista Ghana
vati, chandrakala rasa, Chandraprabha vati, pravaal pisti, Guduchi satva etc
4) Diabetes with cough: Diabetic patient suffering of chronic cough may given powders of Yasti madhu,
Kantakari, Vasa, Shati etc. Ayurvedic cough syrups available in the market are not safe to be taken by a
diabetic patients
5) Diabetes with excessive thirst: Excessive thirst may be managed with the use of cold infusions (heema) of
Dahayanak, usheera, Chandan etc. Praval, Guduchi, may also be used
6) Diabetes with excessive urination: excessive urination can be treated with the use of Trivang bhasma,
jasad bhasma, etc
7) Generalised weakness and fatigue are the usual symptoms that can be treated with the use of herbs like
shatavari, Ashvagandha, Bala Yastimadhu. Complications like tapyadi loha, Vasant kusumakar rasa are also
very effective
8) Impotency is a very distressing symptom of a diabetic patient. By assessing the age of the patient they may
be advised Ashwagandha, Kaucha beeja, musali etc.
Scientific back-up of some extensively researched herbs
GUDMAR (Gymnema sylvestre)
Gymnema sylvestre stimulates insulin release in vitro by increased membrane permeability.
Persaud SJ, Al-Majed H, Raman A, Jones PM.
It appears to correct the metabolic derangements in diabetic rabbit liver, kidney and muscle.
This herbal therapy appears to bring about blood glucose homeostasis through increased serum insulin levels
provided by repair/regeneration of the endocrine pancreas.
Gymnema therapy appears to enhance endogenous insulin, possibly by regeneration/revitalisation of the
residual beta cells in insulin-dependent diabetes mellitus.. This is supported by the appearance of raised
insulin levels in the serum of patients after Gymnema supplementation.
Studies suggest that the component of Gymnema sylvestre inhibits the increase in the blood glucose level by
interfering with the intestinal glucose absorption process
Jamun & Nyagrodha
Hypoglycemic activity of Eugenia jambolana and Ficus bengalensis: mechanism of action.
Achrekar S, Kaklij GS, Pote MS, Kelkar SM.
Biochemistry Division, Bhabha Atomic Research Centre, Bombay, India.
Karella (Momordica charantia)
Ahmed I, Lakhani MS, Gillett M, John A, Raza H
Diabetes Res Clin Pract 2001 Mar;51(3):155-61
Hypotriglyceridemic and hypocholesterolemic effects of anti-diabetic Momordica charantia (karela) fruit extract
in streptozotocin-induced diabetic rats. . These results suggest that M. charantia fruit extract exhibits
hypolipidemic as well as hypoglycemic effects in the STZ-induced diabetic rat.
Bangladesh Med Res Counc Bull 1999 Apr;25(1):11-3
Effect of Momordica charantia (Karolla) extracts on fasting and postprandial serum glucose levels in NIDDM
patients.
Ahmad N, Hassan MR, Halder H, Bennoor KS.
Department of Pathology, Sher-e-Bangla Medical College, Barisal.
wThis hypoglycaemic action was observed in 86 (86%) cases. The results indicated that there was a significant
(Student's t-test, P < 0.004) increase in the number of beta cells in M. charantia-treated animals when
compared with untreated diabetics, however, their number was still significantly less than that obtained for
normal rats.
NEEM
Indian J Physiol Pharmacol 2000 Jan;44(1):69-74 A study of hypoglycaemic effects of Azadirachta indica
(Neem) in normaland alloxan diabetic rabbits.
Khosla P, Bhanwra S, Singh J, Seth S, Srivastava RK.
Hypoglycaemic effect was observed with Azadirachta indica when given as a leaf extract and seed oil, in
normal as well as diabetic rabbits The data suggests that A. indica could be of benefit in diabetes mellitus in
controlling the blood sugar or may also be helpful in preventing or delaying the onset of the disease KIRAT
TIKTA
Swerchirin induced blood sugar lowering of streptozotocin treated hyperglycemic rats.
Saxena AM, Bajpai MB, Mukherjee SK.
Central Drug Research Institute, Lucknow, India.
It has a very significant blood sugar lowering effect in fasted, fed, glucose loaded, and tolbutamide pretreated
albino rat models.
FENUGREEK
Effect of Trigonella foenum graecum (Fenugreek) on blood glucose in normal and diabetic rats.
Khosla P, Gupta DD, Nagpal RK.
Department of Pharmacology, Pt. B. D. Sharma Medical College, Rohtak.
Trigonella foenum graecum (Fenugreek) was administered at 2 and 8 g/kg dose orally to normal and alloxan
induced diabetic rats. It produced a significant fall (P < 0.05) in blood glucose both in the normal as well as
diabetic rats and the hypoglycemic effect was dose related.
Abdel-Barry JA, Abdel-Hassan IA, Al-Hakiem MH.
Department of Chemistry, College of Science, University of Basrah, Iraq.
Hypoglycaemic and antihyperglycaemic effects of Trigonella foenum-graecum leaf in normal and alloxan
induced diabetic rats.
GUDUCHI
Antioxidant activity of Tinospora cordifolia roots in experimental diabetes.
Prince PS, Menon VP.
Department of Biochemistry, Annamalai University, Tamil Nadu, India.
The research is concluded in The effect of Tinospora cordifolia was as effective as glibenclamide. It may be
concluded that extracts of the leaves of Tinospora cordifolia have an insulin-like action and can significantly
reduce the blood glucose in normal rabbits and in alloxan-induced diabetic rabbits.
VIJAYASAR
Indian J Med Res 1998 Jul;108:24-9
An active constituent of Pterocarpus marsupium, (-)-epicatechin (1) in,low doses, has been reported to reverse
hyperglycemia in alloxan diabetic rats when given before or within 24 hr after the dose of alloxan. The
antihyperglycemic activity of ethanolic extract of Vijaysara bark at the dose of 0.25 g/kg b.w. was found to be
more effective than that of glibenclamide and metformin.
Vijayasar is useful in the treatment of newly diagnosed or untreated mild NIDDM patients
HONEY
1) JPMA 39: 107, 1989).
Acta Diabetol Lat 1988 Jul-Sep;25(3):197-203
Oral administration of pure small or large-bee honeys in 5 ml/kg/doses could not produce a significant (P
greater than 0.05) increase in glucose levels in normal and alloxan-diabetic rabbits (Akhtar MS, Khan MS.)
pure natural honeys in low doses may be recommended as a source of carbohydrates and even as a sweetening
agent in place of sucrose to the human patients suffering from diabetes mellitus
Metabolic effects of honey (alone or combined with other foods) in type II diabetics. 1) honey and bread produce
similar degrees of hyperglycemia in type II diabetics. 2) Fat-rich foods added to honey do not alter the total
hyperglycemic effect but result in higher triglyceride and insulin serum concentrations.
2) Samanta A, Burden AC, Jones GR Diabet Med 1985 Sep;2(5):371-3
It is suggested that honey may prove to be a valuable sugar substitute in diabetics, and that both the GI and PI
should be used in the analysis of food.
3) Ionescu-Tirgoviste C, Popa E, Sintu E, Mihalache N, Cheta D, Mincu I.iabetologia 1983 Feb;24(2):80-4
Counting the blood glucose increase after glucose as 100%, the corresponding increases in glycaemia for other
carbohydrates were: fructose, 81.3%; lactose, 68.6%; apples, 46.9%; potatoes, 41.4%; bread, 36.3%; rice, 33.8%;
honey, 32.4% and carrots, 16.1%.
What stages one should expect Ayurvedic Medicines to be effective?
Newly diagnosed mild to moderate diabetic mellitus.
Non-Insulin Dependant Diabetes.
Postprandial Blood sugar should not be very high (below 450-mgm%).
Obese Diabetics.
Uncomplicated Diabetes mellitus.
Those in whom there is a secondary failure: in such cases Ayurvedic drugs can be combined to their regular
allopathic hypoglycemic medicines.
In case of Diabetic Complications some good remedies are available for early nephropathies, neuropathies and
retinopathies. Research is on to find solution to many of these problems of Diabetes.
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Antioxidant Activity and Phytochemical Analysis of Triphala
Posted by on Wednesday, 20th May 2009
ABSTRACT
Ayurvedic formulation triphala was found to be effective in inhibiting γ-radiation induced damage in
microsomal lipids and plasmid pBR322 DNA. The fast reaction kinetic tools like pulse radiolysis and
stopped flow technique were used to asses its antioxidant activities and antioxidant equivalents. The
phytochemical analysis showed that triphala is rich in polyphenols (38± 3%) and tannins (35 ± 3%).
Based on these studies it is proposed that triphala is an effective antioxidant, which can act as a good
radio protector.
DETAILS
Introduction
In the recent past, there has been growing
interest in exploiting the biological activities of
different ayurvedic medicinal herbs, owing to
their natural origin, cost effectiveness and lesser
side effects ].
Triphala is one of the
ayurvedic medicinal herbal formulations
prescribed by most health care practitioners.
It isused as colon tonic, laxative, eye rejuvenator,
anti-inflammatory, anti-viral etc.
It is a composite
mixture of three medicinal herbs Amalaki
(Emblica officinalis), Haritaki (Terminalia
chebula) and Bibhitaki (Terminalia belerica).
Triphala is gentle for people of all ages, from
children to seniors and hence is recommended
for everybody [3].
Triphala has been tested as
an antioxidant and also as a radioprotector in
mice [4, 5]. In the present study, we tested the in
vitro antioxidant activity under γ-radiation
induced conditions.
In order to understand the
factors responsible for the antioxidant and radio
protection activity, free radical reactions and
phytochemical analysis of triphala were carried
out.
Experimental
Lipid peroxidation in microsomes and DNA
damage in pBR322 were carried out using 60Co
γ-source [2].
Nanosecond pulse radiolysis and stopped flow technique were used to study rates
of free radical reaction and to determine the
antioxidant equivalents. Phytochemical analysis
were carried out by using HPLC and absorption
spectrophotometry.
Results and Discussion
The aqueous extract of triphala (20 μg/ml)
inhibited γ-radiation induced lipid peroxidation in
rat liver microsomes at all the doses employed
(120 – 360 Gy) to the extent of 65 to 85%. By
using concentration profile studies (5-35 μg/ml)
at a fixed dose of 240 Gy, IC50 value of 10μg/ml
was determined.
Triphala (25-200 μg/ml) was also found to be effective (~35-75%) in inhibiting
γ-radiation induced (absorbed dose of 6 Gy)
strand breaks in plasmid pBR322 DNA
The above two studies suggest that triphala
exhibits antioxidant activity under γ-irradiation
conditions. Under these conditions, damage to
biomolecules is initiated by the free radicals
produced by the radiolysis of water. Hence it is
appropriate to study their free radical scavenging
ability.
Free radical reactions of Triphala
The radical scavenging experiments were
carried out by using fast reaction kinetic tools
like pulse radiolysis and stopped flow technique
and the reactivity of triphala towards different
radicals such as hydroxyl radicals, superoxide
radicals, DPPH and ABTS•− were determined.
Triphala was found to be an effective scavenger
of DPPH and superoxide radicals.
The reaction of ●OH with triphala, produced a
transient absorbing in the region 350 – 500 nm
with a major transient absorption peak at 350 nm
attributed to gallic acid type of radicals.
Phytochemical analysis
Phenolic acids, flavonoids and tannins are the
most commonly found polyphenolic compounds
in the plant extracts. In the present studies we
have estimated the total polyphenolic and tannin
content in triphala by using Folin- Ciocalteau
method and Folin-Denis method respectively.
It showed that triphala contains 38± 3%
polyphenols and 35 ± 3% tannins. The HPLC
analysis was carried out by using a C18 PCX
500 analytical column and mobile phase (0.05 M
HCl, 0.1 M KCl and varying the percentage of
acetonitrile from 2.5 – 32 %). The detector used
for HPLC analysis is a UV detector set at 260
nm.
It showed that triphala contains sufficient amount
of gallic acid (Figure 2), so that it can be used as
marker compound for in-vivo studies.
Conclusions
Triphala, a well known ayurvedic formulation,
exhibits antioxidant activity and radio protection
ability under in vitro conditions The polyphenolic
content in triphala confirm that the antioxidant
and radioprotecting ability of triphala arises from
the polyphenols, which reduce oxidative stress
by converting the reactive oxygen free radicals
to non-reactive products. The studies are of
great significance as the demand for herbal
products as antioxidants and radio protectors is
increasing constantly.
( SOURCE -- Founder’s Day Special Issue, 2005)
Note - The aim of this article is to increase awareness in Ayurvedic community about
wonderful uses of ayurvedic drugs , and to enhace use of evidence based medicine.
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AYURVEDIC HOME REMEDIES
Posted by on Wednesday, 20th May 2009
HOME REMEDIES FOR SOME COMMON PROBLEMS
URTICARIA
Ayurvedic Synonym : - Shitapitta
Main symptoms : –
1. Rash all over the body.
2. Itching.
3. Reddish patches.
Remedies :-
1. Piper nigrum (Marich) with cow’s ghee.
2. Curcuma longa (Haridra) powder with milk or hot water.
3. Application of bark of (Kapitha).
Ayurvedic Medicines : -
1. Brihat Haridra Khand Yoga.
2. Khadirarishta.
3. Mahamanjishthadi kwath.
4. Arogyavardhini.
CONSTIPATION
Ayurvedic Synonym : - Malavashtambha
Main symptoms : –
1. Irregular bowel evacuation.
2. Passage of hard stool in less quantity.
3. Flatulence.
Remedies :-
1. 10-15 pieces of Vitis vinifera (Black Grapes) kept over night in a glass of water and used at morning can relive constipation permanently.
2. Decoction of Zingiber officinale (Ardrak) added with 2 or three teaspoon of castor oil, taken at bedtime can be useful for chronic constipation.
3. Powdered Terminalia.chebula (Haritaki) processed in cow’s ghee in the dose of 1 teaspoon followed by lukewarm water is also proved as equal effective.
Ayurvedic Medicines : -
1. Avipattikar churna.
2. Gandharva Haritaki churna.
3. Argwadh kapila vati.
4. Abhayadi Modak
VOMITTING
Ayurvedic Synonym : - Chhardi
Main symptoms : –
1. Nausea
2. Ejection of stomach contents.
Remedies :-
1. Glycyrrhiza glabra (Yashtimadhu) + Pterocarpus santalinus(Raktachandan } paste prepared in milk.
2. Santalum album (Chandan) + Emblica officinals (Amalki) } with honey
3. Fresh juice of Punica granatam(Dadim)
4. Decoction of Coriandrum sativum (Dhanyak) with honey mixed.
5. Fresh juice of Zingiber officinale (Ardrak)+ Allium cepa (Palandu).
Ayurvedic Medicines : -
1. Sutshekhar ras
2. Pravalpanchamrit
3. Mayur-pichhamashi
4. Chandanadi loha.
5. Dadimavaleham.
INDIGESTION
Ayurvedic Synonym : - Ajirna
Main symptoms : –
1. Loss of appetite
2. Nausea with /without vomiting.
Remedies :-
1. Citrus acida (Nimbuk) + Zingiber officinale (Adrak) + Salt (Saindhav) + Allium sativum (Rason) } Mixture - before meals
2. Tea of Syzygium aromaticum (Lavang) is effective when there is nausea and loss of appetite.
3. Ferula narthex (Hingu) with cow’s ghee.
4. Carum roxburghianum (Ajmoda) and salt (Saindhav) with hot water.
5. Drinking of Hot water intermittently.
6. Cuminum cyminum (Jirak) with Buttermilk.
Ayurvedic Medicines : -
1. Hingvashtak churna.
2. Panchakolasav
3. Shankhavati
4. Lavanbhaskar churna.
HAIR LOSS
Ayurvedic Synonym : - Khalitya
Main symptoms : –
1. Progressive hair fall with or without dandruff.
Remedies : -
1. Gentle massage with
coconut oil.
Sesamum oil processed with Emblica officinals (Amalaki) and Bacopa monnieri (Brahmi).
2. Emblica officinals (Amalki) Cyperus rotundus (Musta) Sapindus trifoliatus (Arishtak) } Rinsing hairs with decoction of these herbs.
3. Triphala churna + Black Sesamum + Eclipta alba (Bhringaraj) } powder with hot water of internal use.
4. Massage with pulp of Aloe vera (Kumari) and Hibiscus rosa-sinensis (Japa-kusum).
Ayurvedic Medicines : -
1. Bhringaraj ghan vati
2. Asthiposhak vati
3. Arogyavardhini
4. Praval panchamrit.
5. Tikta ghrit.
JOINT PAIN
Ayurvedic Synonym : - Sandhigata Vata
Main symptoms : –
1. Painful joints with or without inflammation
2. Restricted movements of joints.
3. Increased local temperature in inflamed joints.
Remedies :-
Inflamed joints :-
1. Dry fomentation.
2. Apply poultice of smashed leaves of Allium sativum (Rason), Ricinus communis (Erand), Vitex negundo (Nirgundi) Mixed with salt.
3. Zingiber officinale (Ardrak) ,Curcuma longa (Haridra) in paste form for Local Application.
Non Inflamed joints :-
1. Gental massage with Sesamum oil followed by hot water fomentation.
2. Smashed Allium sativam (Rason) boiled in milk.
Ayurvedic Medicines : -
Inflamed joints :-
1. Sinhanad guggul
2. Punarnava guggul
3. Dashamularishta
4. Rasnasaptak kwath
5. Mahavishagarbha tail for Local application
Non inflamed joints :-
1. Mahayograj guggul.
2. Mahanarayan tail for Local Application
3. Ashwagandharishta.
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