AIDS/ HIV HIGH PREVALENCE IN INDIA :UN DECLARATION ZERO HIV / ZERO DISCRIMINATION BY 2015
Posted by on Tuesday, 11th March 2014
AIDS:UN DECLARATION ZERO HIV / ZERO DISCRIMINATION BY 2015
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There are 22 priority countries; they have the highest number of pregnant women living with HIV, as recognised in the ‘Global Plan towards the elimination of new HIV infections among children by 2015 and keeping their mothers alive’.Global plan was formulated by 110 countries of World in UN HQ by formulating 10 TARGETS ,THE GOAL TO BE COMPLETED BY 2015 WITH YEARLY SURVEILLANCE AND MONITORING OF PROGRAMME AND ITS SUCCESS AND HINDRANCE to combat hiv/aids spread,contamination and new cases to promote zero tolernce for hiv/aids,no new cases or ZERO HIV NEW INFECTION AND DEATH DUE TO AIDS by good funding of screening every person for HIV/AIDS and providing primary and secondary treatment for every infected person in countries like india,and other sian countries and countries of AFRICA AND LATIN AMERICA and to extend insurance sector to HIV /AIDS IN USA BY PRESIDENT PROFAR PROGRAMME,ZERO DISCRIMINATION OR STIGMA for HIV LIKE A BILL IN UPPER HOUSE IN INDIA to punish those who discriminate HIV /AIDS.
These 22 countries are: Angola, Botswana, Burundi, Cameroon, Chad, Côte d’Ivoire, Democratic Republic of the Congo, Ethiopia, Ghana, India, Kenya, Lesotho, Malawi, Mozambique, Namibia, Nigeria, South Africa, Swaziland, Uganda, United Republic of Tanzania, Zambia, and Zimbabwe. India is the only country not in Africa.
10 TARGETS SETS UNIVERSALLY TO COMBAT HIV/AIDS WITH SPECIAL FOCUS ON ABOVE 22 COUNTRIES ARE AS FOLLOWS:-----.
1.Reduce sexual transmission of HIV by 50% by 2015
2.Halve the transmission of HIV among people who inject drugs by 2015
3.Eliminate HIV infections among children and reduce maternal deaths
4.Reach 15 million people living with HIV with lifesaving antiretroviral treatment by 2015
5.Halve tuberculosis deaths among people living with HIV by 2015
6.Close the global AIDS resource gap
7.Eliminate gender inequalities and gender-based abuse and violence and increase the capacity of women and girls to protect themselves from HIV
8.Eliminate HIV-related stigma, discrimination, punitive laws and practices
9..Eliminate HIV-related restrictions on entry, stay and residence
10.Strengthen HIV integration — with Sikkim Aids Empl Assocn and 15 others. (4 photos)
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HIV / AIDS: CONTRACEPTIVE & HIV PREVENTING VAGINAL RING DISCOVERED,BEING USED TO PREVENT PREGNANCY & HIV
Posted by on Monday, 10th March 2014
HIV / AIDS: CONTRACEPTIVE & HIV PREVENTING VAGINAL RING DISCOVERED,BEING USED TO PREVENT PREGNANCY & HIV
PROF.DRRAM ,HIV/AIDS,SEX DIS.,SEX WEAK.& ABORTION SPECIALIST
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HIV/ AIDS,CANCER LATEST MEDICINES AVAILABLE AT CHEAP RATE.
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AN INTRAVAINAL RING HAVING LOADED MEDICINES TENOFOVIR (AN HIV ARV NRIT MEDICINE) AND LEVONORGESTREL (A CONTRACEPTIVE) has been developed by Northwestern University biomedical engineer Patrick Kiser .This is first-of-its-kind intravaginal ring 'reliably delivers' an antiretroviral drug and a contraceptive for months.
The device is designed to protect against HIV and herpes as well as unwanted pregnancy. It will be the first device with the potential to offer this protection to be tested in women.
According to the World Health Organization, 35 million people around the world live with HIV, and 222 million women would like to delay or stop childbearing but are not using any method of contraception.“I suspect women will use the ring primarily for contraception, but they also will benefit from protection against sexually transmitted diseases,” said Kiser, an expert in intravaginal drug delivery. “And for women in the developing world in particular, unwanted pregnancy can have significant health, economic and cultural consequences. We want to motivate women to use this ring.”
The ring, 5.5 centimetres in diameter, is simple yet complex. Kiser and his colleagues worked painstakingly for five years, engineering the three materials that make up the ring and optimizing the device to reliably deliver fixed and efficacious doses of two medicines over a long period of time.the ring is easily inserted in the vagina and stays in place for three months. And because the tenofovir is delivered at the site of transmission, the ring – known as the tenofovir levonorgestrel IVR – utilizes a smaller dose than pills. The levonorgestrel released by the ring is the same drug as that used in certain contraceptive pills and in an intrauterine device.
Tenofovir is taken orally by 3.5 million HIV-infected people worldwide, and it also has been studied as a gel. The drug inhibits HIV and HSV-2 (herpes simplex virus-2) replication in susceptible cells.
Previous studies have demonstrated that antiretroviral drugs can prevent HIV infection, but existing methods for delivering the drug fall short. Pills must be taken daily and require high doses; some women may prefer a longer-lasting method, such as the ring, versus methods used at the time of sex, such as a gel.
The antiretroviral drug section of the ring is made of one kind of polyurethane, and the contraceptive section of the ring is made of another polyurethane. Each material needed to be engineered with the correct diffusion rates, so the encapsulated drug is released into the body at the desired rate, providing the correct dose.
A third polyurethane material between the two sections keeps the drugs separate. All the parts are welded together to complete the ring.
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HIV /AIDS: ARV MEDICINES : SOME TRUTHS & MYTHS OF TREATMENT FOR HIV /AIDS PATIENTS FOR BETTER ADHERANCE & CURE
Posted by on Monday, 10th March 2014
HIV /AIDS: ARV MEDICINES : SOME TRUTHS & MYTHS OF TREATMENT FOR HIV /AIDS PATIENTS FOR BETTER ADHERANCE & CURE
PROF.DRRAM ,HIV/AIDS,SEX DIS.,SEX WEAK.& ABORTION SPECIALIST
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HIV/ AIDS,CANCER LATEST MEDICINES AVAILABLE AT CHEAP RATE.
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Antiretroviral therapy -- or ART -- A COMBINATION OF 3-4 DRUGS COMPRISING OF EITHER NRIT OR NNRITS WITH PROTESE INHIBITOR WITH FUSION OR INTEGRASE INHIBITOR OR RECEPTOR BLOCKE revolutionized HIV treatment in the past few decades. And newer improvements, like one-pill-a-day drugs,or injections once a quarter as i wrote in my last article,are making life with HIV easier and safer.
Like chronic disease as hypertension,Diabetes,thyroid or Kidney or cancer we have to take this medicines regularly without any fail and if we do so we shall get Viral load or quantity of virus in our body decreses and our defense cell cd4 population rises and we live a normal life and no opputunistic infections like tb,diarrhoea,skin rashes,ulcers or mouth lesion or fungal infection attacks us.decision to which drug to be used is a complcated one and only an experienced doctor keeping details of type of patients,exposures and presence of infections and general condition of patients and personal history of pt and economical conditions all gives input to DOCTOR TO SELECT DRUG ON EXPERIENCE and DOCTORCHANGES IT IF RESPONSE IS NOT COMING OR ADD SOME MORE IF OPPUTUNISTIC OR OTHER SYMPTOS DEVELOP.
SO SELF MEDICATION OR MEDICATION ONSIMPLE NET OR TELEPHONIC ADVICE ARE DANGEROUS AND SHOULD BE NEVER TAKEN.TILL NOW ALTERNATIVE HERBAL MEDICINES EFFICACY IS NOT PROOVED SO NEVER TRUST THEM AND AVOID THEM EXCEPT SOME VITMINS,FOOD SUPPLEMENTS AND EXCERCISES.
5 Things to Know About HIV Medications;--
There are lots of myths and stale, outdated information about HIV treatment. Here are five things you should know about ART.
It's easier to take than it used to be. A lot of people with HIV just take one pill once a day. That's it. That one combination pill -- Atripla, Complera, or Stribild -- packs in all the different active ingredients you need. Most people don't need the "cocktails" with complicated dosing schedules anymore.
You have lots of options. Some people need drug combinations. There are six classes of antiretroviral drugs for HIV and more than 30 drugs. If one doesn't work or causes side effects, the doctor has many other choices.
Medications work for a long time. People used to worry that their drugs would stop working after a while and that they'd have to keep switching to new ones. That's not really a risk now. "As long as you keep taking your medications, the same treatment can work for decades," Hare says.
Drugs have fewer side effects. While specific side effects depend on the drug, HIV treatment is much safer and easier to tolerate than it used to be. For most people, side effects -- like upset stomach and diarrhea -- are minor and often go away. Long-term risks include cholesterol problems and weakened bones. But even so, the risks of treatment are much lower than the risks of not getting it, Hare says.
You may start taking medication as soon as you're diagnosed. Many experts believe that the sooner you start treatment, the better. However, some doctors prefer to wait until your CD4 count, a measure of some immune cells, drops to a certain point before starting treatment. See what your doctor recommends.
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HIV AIDS: LONG ACTIVE ONCE IN A QUARTER MEDICINE IS ON WAY: BETTER COMPLIANCE AND ADHERANCE LESS SIDE EFFECTS
Posted by on Sunday, 9th March 2014
HIV AIDS: LONG ACTIVE ONCE INA QUARTER MEDICINE IS ON WAY :
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A long-acting, injectable HIV drug could potentially protect people from infection with the AIDS virus for up to three months, new animal studies suggest.The experimental drug, called GSK744, protected macaque monkeys from repeated attempts to infect the animals with a hybrid simian/human AIDS virus called SHIV, scientists said.
GSK744 is a reformulated, long-acting version of an HIV drug known as dolutegravir (Tivicay), which has been approved by the U.S. Food and Drug Administration for treatment in people who have already been infected with HIV and is now used in many combination as primary or secondry drug in USA AND UK but not IN OUR ART CENTRES .these are less toxic and having less side effects and reisitant to virus is almost unknown.
While GSK744 hasn't been tested on humans, doctors hope that it will lead to a medication that could effectively protect people against HIV infection, mostly because it would only need to be administered on a quarterly basis. However, findings from animal studies often don't hold up in human trials.
Such a long-lasting drug would help overcome one of the major problems with current medications that attempt to protect against HIV infection -- the ability of people to take their medication on a daily basis.
"Some of the really good pre-exposure prophylaxis treatments have not been effective, mainly because people don't take the drug," said Dr. Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases. "The major stumbling block the field has experienced has been the lack of adherence. It's not because the drugs don't work. It's because people don't take them as directed."
Researchers expect to launch human trials for GSK744 within a matter of months, said study author Chasity Andrews, a scientist with the Aaron Diamond AIDS Research Center at Rockefeller University in New York City.
GSK744 is in a class of antiretroviral drugs called integrase inhibitors. These medications block HIV from inserting its genetic material into the body's immune cells.
GSK744 is different in that it crystallizes in the bloodstream, allowing a slow, steady release of the medicine over time, the Rockefeller researchers explained.
Their findings are published online March 6 in the journal Science. The Rockefeller study, and similar results from a study conducted by researchers at the U.S. Centers for Disease Control and Prevention, were presented Tuesday at the annual Conference on Retroviruses and Opportunistic Infections in Boston, according to published reports.
The medication levels that protected the monkeys translate to doses that could sustain human protection for 12 weeks to 16 weeks, Andrews said.
Effective protection against HIV is necessary to fight the spread of AIDS. There were 2.3 million new HIV infections globally in 2012, the researchers noted in background material, with more than 35.3 million people already infected. — with AidsControl Empl India and 19 others.
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HIV /AIDS :CAUSTIONS BEFORE AND AFTER TREATMENT:MEDICINES SHORT & LONG TERM SIDE EFFECTS & MANAGEMENT
Posted by on Sunday, 9th March 2014
HIV /AIDS :CAUSTIONS BEFORE AND AFTER TREATMENT
PROF.DRRAM ,HIV/AIDS,SEX DIS.,SEX WEAK.& ABORTION SPECIALIST
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HIV/ AIDS,CANCER LATEST MEDICINES AVAILABLE AT CHEAP RATE.
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HIV /AIDS only methos to control it is by medicines ARV ,mostly a combination of recently investigated and discovered 3-4 medicines WHICH CURES VIRUS BUT PRODUCE MANY SIDE EFFECTS,SO SHOULD BE TAKEN AFTER PRECRIBED BY A GOOD EXPERT DOCTOR,self or over the table or counter medicines may produce many lethal side effects and complications.
doctors write thesr medicines specifically needed for one person or individually as his way of exposure,duration of symptos,presence of any oopurtunistic infections,his blood tests like CD$,Viral Load,CBC,LFT,KFT, LIPIDPROFILE, HBSag,HCV,VDRL,urine R/E,urine C/S,Stool for R/E ,CXR,ECG,USG of Abdomen etc are main tests needed to be done before starting therapy as presence of ny TB,STDs,Pneumonia,Diarrhoea or skin rash may produce unlike effects and complications and so medicines will change from one person to other considering his /her food habit,any addiction history,physical built,personal history of excercise and mental status and attitude.
Short-Term Side Effects of HIV Treatment:
HIV treatment can cause side effects for a brief period while it is controlling the virus in your body. Common short-term side effects include:
Fatigue
Anemia, a problem with red blood cells that may also cause fatigue
Diarrhea, nausea, or vomiting
Dizziness or headaches
Insomnia
Pain and nerve problems
A skin rash
Injection site reactions
Dry mouth
Weight loss
Vivid dreams
Although these side effects may bother you for a while, they frequently get better with time -- often within a few weeks.If side effects do not lessen, or if they are severe or unusual, then Doctor will decide whether to continue medicines or not as Heapatitis leading to high jaundice or severy skin rashes as Stevns Jhonson syndrome or severe depression or loss of sleep or night mares,so severe anaemia or lipidostrophy may bound him to stop some medicines and start new mediicines..
Doctor examines that CD$ rises and Viral load decreases if not then he suspects Viral Resistant with medicines so if affordable drug sensitivity test or otherwise randomly he stars new medicine out of one group.During this one has to take medicines regularly without any fail,good diet,excecise,and no addiction of alcohol,nicotine,drugs and good sexual habit with safe sex and no contamination with infected blood or semen.
Coping With Long-Term Side Effects of HIV Treatment:
Some of the most common long-term side effects and coping strategies include:
Fat redistribution. Known as lipodystrophy, this can occur when the body changes the way it produces, uses, and stores fat. You might lose fat in your face and legs and gain fat in your abdomen and back of your neck. Switching medications may keep symptoms from getting worse. But there are few other options for treating this long-term side effect.
Increases in cholesterol or triglycerides. This can increase the risk for problems such as heart disease. Diet and other lifestyle changes are a first step. Medications such as statins and fibrates may also be recommended by your doctor.
Elevated blood sugar levels. Exercise, weight management, and other lifestyle changes may help. Your doctor may also recommend other medications to control blood sugar levels.
Decreases in bone density. This can increase the risk of bone fractures, especially as you get older. Try weight-bearing exercises like walking or weight lifting. Your doctor may recommend calcium and vitamin D supplements, or medications to treat or prevent osteoporosis.
A buildup of a cellular waste product. Known as lactic acidosis, this uncommon issue can cause a wide range of problems, from muscle aches to liver failure. You may need to switch drugs.kidney stones can also occur so one has to take more water intake,side by side if any oppurtunistic infection then Cotraimaxazole for Pneumonia,Dirrhoea,toxoplasma ,cytomegal onfection,anti fungal for fungal infection and treatment for TB etc has to be taken.During start of such treatment "IRIS" or a special reaction may develop but subsides with steroid and regular treatment .
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