Blastocyst embryo transfer (BET) is a new assisted reproductive technology that has been incorporated with in vitro fertilization (IVF) treatment to increase pregnancy rates while simultaneously decreasing the risk of multiple pregnancies. In vitro fertilisation usually involves the transfer of embryos two to three days after they have been successfully fertilised. Blastocyst Culture and Transfer is a technique in which an embryo is developed in the laboratory for 4-6 days after fertilisation before being placed in womb. The embryo gains many cells as a result of being developed for so many days. The embryos developed for 4-6 days are much more advanced than the ones developed for just three days. These Embryos are called blastocysts. BET helps reduce the incidence of multiple gestation pregnancies by transferring fewer embryos.

What is Blastocyst culture?

Until recently, successfully culturing embryos to the blastocyst stage was difficult. This term describes the process when the embryos grow for longer in the laboratory, and undergo critical developmental changes before being returned to the womb. Scientific advances have led to the development of culture media that mimic the changing environment of the reproductive tract and meet the unique requirements of the embryo as it travels from the fallopian tubes. This now allows up to 60% of embryos to successfully grow to the blastocyst stage in the laboratory environment. This period of extended culture helps experts to select the most competent embryo (s) for transfer to your womb. Therefore, blastocyst culture maximises the chance of you achieving a viable pregnancy. During the additional two days of in vitro culture (day 3 to 5), the embryologists have an opportunity to observe embryonic development and to select those embryos which appear to have the best potential for continued growth and implantation. Although this period of extended culture doesn’t necessarily improve the quality of the embryos, or guarantee that they reach the blastocyst stage, there are impressive success rates available for this treatment.

Learn from the experts in IVF field about Blastocyst Embryo Transfer, its advantages, disadvantages and risk associated with the treatment at http://indiraivf.com/services/blastocyst-culture-and-transfer/

What is the procedure involved into Blastocyst embryo transfer?

During IVF treatment with blastocyst transfer, unfertilized eggs (oocytes) are retrieved from the ovary. They are then fertilized in an IVF laboratory setting, creating an embryo. Instead of being transferred to the uterus after three days, which is the case during traditional IVF treatment, the embryos are allowed to progress to the blastocyst stage over a period of five to six days. During unassisted fertilization, the embryo must reach the blastocyst stage in order to attach to the uterine wall. Because, during blastocyst transfer IVF, the embryos are implanted in the uterus during this same stage of development, some consider this to be a more natural implantation method. Blastocyst transfer mimics natural conception in which the embryo travels down the fallopian tube and reaches the uterine cavity five days after fertilisation. This synchronises the development of the embryo and the lining of the womb to increase the chance of implantation. Only healthy embryos are selected for transfer.

For whom is Blastocyst Embryo Transfer Recommended?

Blastocyst transfer is not suitable for everyone. It is a laboratory selection process to identify the best embryo. Couples who have had unsuccessful prior attempts with IVF or IVF and ICSI treatment despite having many good quality eggs retrieved are being offered Blastocyst Culture as an alternative treatment. Couples with multiple good quality embryos on day 3 are also good candidates for Blastocyst Culture. The ability to select the most viable embryos for transfer and implantation should improve their chance of achieving a pregnancy. Blastocyst transfer is not an option for all IVF patients. The technique is most successful with patients who are younger and have a large number of eggs available at retrieval. On average, patients with six or more high quality embryos on day three are the best candidates for blastocyst culture because there is a better chance of more embryos growing successfully till day five.

Frozen Blastocyst Transfer (FBT)

There is a chance that you may have some blastocysts (advanced five to six day embryos) available for freezing (using a process called vitrification) after you have had your best embryo (s) transferred. Freezing and warming can cause damage to the cells of blastocysts, particularly those which are not good quality. For these reason only very good quality blastocysts embryos are selected for freezing. Having blastocysts frozen means that you can undergo future cycles of IVF without having to stimulate your ovaries, collect and fertilise your eggs. Instead we can warm the frozen blastocyst (s) and transfer them to your womb in a much more simplified frozen blastocyst warming cycle. Your chance of becoming pregnant following replacement of frozen warmed blastocysts is comparable to that following replacement of fresh embryos. There is no evidence that any babies resulting from warmed blastocysts have an increased risk of abnormality.

Advantages of blastocyst transfer

Although you can choose to have the embryos transferred on the third day after fertilization, a blastocyst transfer has many obvious. The first is that it makes it easy to weed out the healthy embryos from the abnormal ones without spending for expensive screening procedures. Studies show that embryos that do not reach the blastocyst stage are more likely to have abnormal chromosome numbers, which means they would have eventually miscarried. Doctors observed that as much as 40% of embryos fail to make it to the blastocyst stage. Thus, waiting for the embryos to reach the blastocyst stage decreases the number of abnormal embryos, leaving you with the ones that are most likely to develop into a healthy baby. The fact that the embryo has already hatched out of its shell also gives it an improved implantation rate. In fact, blastocyst embryos have a 50 % chance of implantation. This means you will only need to have one or two blastocysts transferred, leaving you with a few back up embryos just in case this cycle fails. Spare blastocyst embryos may be cryopreserved until they are needed in the future. Another advantage of developing all embryos to the blastocyst stage is that it makes embryo cryopreservation (freezing) more efficient, since embryos without the capacity for full development are not frozen. Blastocyst transfer also allows the option of single embryo transfer.

Solution to all infertility related treatments including IVF, ICSI, IUI and others and the newly introduced technique Blastocyst Transfer can be obtained at https://indiraivf.wordpress.com/category/blastocyst-embryo-implant

What are the disadvantages of blastocyst transfer?

Although blastocyst embryo transfer increases your chance of getting pregnant, it also increases the risk of multiple births. It is more difficult for an embryo to develop into a blastocyst. Therefore, there is the possibility that an IVF cycle will not result in a transfer of any embryos if none of the three day old embryos develop into blastocysts. The other disadvantage of the procedure has to do with cryopreserving the remaining embryos. Blastocysts cannot survive the freezing and thawing process as well as day 3 embryos do, and you might end up losing most or all of the embryos in the process.

Risks of IVF blastocyst transfer

The primary risk of attempting blastocyst transfer is that some embryos will die in the laboratory. Therefore, the total number of embryos available for transfer and freezing will be less. Unfortunately, some couples undergoing blastocyst ivf treatment will have all their embryos die in the laboratory and will not have any embryos available for transfer. BET does not guarantee a normal pregnancy. It is expected that some pregnancies will miscarry and some babies will develop birth defects similar to that which occurs in couples that are able to achieve pregnancy naturally. Excess blastocysts may be frozen and some of them will not survive the freeze-thaw process when utilized for a later attempt at achieving pregnancy. This is a similar risk to transferring embryos at earlier stages.

In this field of medicine, continued refinements and change offer greater opportunity for infertile couples. Blastocyst culture is one important step and one at which specialists at Indira Infertility Clinic has expertise. We offer our patients this promising state-of-the-art technique, as it provides us the ability to balance the success versus risk in favour of couples, when we assist them in their pursuit of parenthood says Dr. Ajay Murdia, Scientific director at Indira IVF Clinic. Our doctors and embryologists will advise on whether blastocyst transfer is possible and this will depend on the number and quality of embryos available on day 3. Otherwise normal IVF is recommended. Whether day 5 or 6 transfer is recommended for you, it is a decision made by the experienced and expert clinical and laboratory teams aligned to give you the best individualized advice for a safe and successful outcome. Let us help you decide your journey of parenthood.

You can contact the team of experts at Indira IVF at http://indiraivf.com/ or you can fix up an appointment with us at 0 766 500 9965

Endometriosis is a painful, chronic disease that affects more than 176 million women (and their families) worldwide. It occurs when tissue like that which lines the uterus (tissue called the endometrium) is found outside the uterus -- usually in the abdomen on the ovaries, fallopian tubes, and ligaments that support the uterus; the area between the vagina and rectum; the outer surface of the uterus; and the lining of the pelvic cavity. Other sites for these endometrial growths may include the bladder, bowel, vagina, cervix, vulva, and in abdominal surgical scars. Less commonly they are found in the lung, arm, thigh, and other locations.

Endometriosis can cause painful periods, persistent pain in the pelvic area, infertility, and other symptoms. The symptoms can range from mild to severe. Treatment options include painkillers, hormone treatments, and surgery with laparoscope.

Learn in detail about the laparoscopic surgery treatment of endometriosis at http://indiraivf.com/services/laproscopy-hysteroscopy/

Endometriosis is difficult to understand and there are no specific causes which lead to endometriosis. Doctors do not know what causes endometriosis – there may be several causes. From a woman’s perspective, endometriosis is a disease surrounded by taboos, myths, delayed diagnosis, hit-and-miss treatments, and a lack of awareness, overlaid on a wide variety of symptoms that embody a stubborn, frustrating and for many, painfully chronic condition. It affects these women during the prime of their lives and through no personal failing in lifestyle choices. These women’s physical, mental, and social well-being is impacted by the disease, potentially affecting their ability to finish an education, maintain a career, with a consequent effect on their relationships, social activities, and in some cases fertility. About half of women with endometriosis will also suffer from pain associated with sexual intercourse.

These women’s access to timely diagnosis and treatment should not be impacted by the myths and misconceptions that are, unfortunately, prevailing at large.
Let’s discuss here the Myths, Misconceptions and the Facts about endometriosis.

1. Severe pain during period is normal. MYTH

The nature and intensity of the pain associated with endometriosis can vary. Pain might be intermittent or continuous in nature, usually occurring before and during menstruation, and during or after sexual activity. The location and level of pain may not always directly relate to the extent of visible endometrial growths. Some women with extensive visible endometrial growths may be entirely pain free, while others with a few small growths experience severe pain.
Even though attitudes towards women improved during the twentieth century, some of the old beliefs still linger unconsciously, and affect the medical profession’s attitudes towards women’s complaints, including period pain. As a result, while seeking help for their period pain, many women with endometriosis are told that their (severe) period pain is normal and is part of being a woman or it is in their head. Others are told that they have a low pain threshold, or are psychologically inadequate. Many women and girls do experience pain at the time of their period. However, severe pain that interferes with daily life is not normal, and is often due to the presence of an underlying condition, such as endometriosis. Any girl or woman with severe period pain should be investigated to determine the cause of her pain.

2. Endometriosis occurs exclusively in women of reproductive age. MYTH

3. Hormonal treatments cure endometriosis MYTH

4. Pregnancy cures endometriosis MYTH

5. Endometriosis means infertility MYTH

6. Hysterectomy cure endometriosis MYTH

Read the detailed article on Myths and Misconceptions prevailing in the society about endometriosis and educate yourself about the same at https://indiraivf.wordpress.com/2015/03/18/myths-about-endometriosis

No one is certain what causes endometriosis, although researchers believe that genetics, a dysfunctional immune system, hormones, and environmental factors may all play a part in it. According to the Endometriosis Foundation, a woman (or girl) with a mother who has endometriosis is seven times more likely to have the disease herself.

If you’ve suffered with endometriosis for any length of time, chances are you’ve had plenty of advice from people, and chances are that only few of them were helpful. One of the many problems with being an endometriosis sufferer is that people keep on giving opinions which they feel need to share with you despite the fact that at times they also does not know what they talk. At this point it is necessary to keep all old wives tales aside and seek the intervention of Endometriosis specialist. Educating yourself and others about endometriosis is an empowering endeavour and, if you suffer from endometriosis, a necessity. The more you know, the stronger you are, know the evidence, uncover the truth, and ignore the bullshit.

Indira IVF centre is the pioneer in providing affordable yet creditable infertility treatment to the common people for the first time in India. The clinic has the latest state-of-the-art infrastructure, advanced equipments and a pool of renowned physicians. We are deeply committed to provide all the primary and ancillary services related to your treatment under the same roof because we understand the significance of a concerted, meticulous and well-oiled network for your pregnancy success. With the advent of the cutting edge technology our OB-GYN specialists carry out Laparoscopy and Hysteroscopy surgeries which are used to diagnose and cure certain female infertility conditions. Laparoscopy is done to determine the causes of infertility, symptoms like pelvic pain & abdominal pain and to check if there are any scar tissues or blockage in the fallopian tubes. The doctors use this technique to treat cysts, endometriosis and fibroids.

You can contact our team of fertility and infertility specialist at http://indiraivf.com or fix up an appointment to meet at 0 766 500 9965

Know all about Male infertility - Male reproductive system -Male fertility - Male infertility causes - Male reproductive system and infertility - Causes of male infertility & Male fertility test - Male infertility symptoms and Male infertility treatment - Male infertility - male fertility supplements - male fertility drugs - How to increase male fertility - Male sterility - Male factor infertility

Causes of infertility or reproductive problems include disease and aging. Male infertility is as common as female infertility. Infertility or reproductive problems are often treatable with infertility drugs and high-tech procedures. A third of all cases of infertility involve problems solely with the male partner. Infertility in a man may be the sole reason that a couple can't conceive, or it may simply add to the difficulties caused by infertility in his partner. Early testing for male fertility can spare their partners a great deal of unnecessary discomfort and expense. It's also a good way to quickly narrow down potential problems.

Men can remain fertile for much longer than women. Even though male fertility also declines with age, it tends to happen gradually for men. While many men remain fertile into their 50s and beyond, the proportion of men with sperm disorders increases with age. The decline in male fertility is more gradual for men than women. The decline in male fertility can affect the health of the children they may go on to have.

While female age is well known to have negative effects on fertility, reproductive success and the health of offspring, the influence of male age on a couple's fertility has been largely neglected all over the world. It is well recognised that reduced sperm performance can affect pregnancy success, but it is less well known that the quality of the sperm, particularly DNA quality, could affect the development and health of the offspring. The consistency in its findings suggests that further awareness of the potential consequences of male age on reproductive outcomes is needed. The study also establishes that older males contribute to increased risk of obstetric complications, miscarriage, and offspring disorders such as autism, Down syndrome, epilepsy, and schizophrenia.

Male infertility is due to low sperm production, abnormal sperm function or blockages that prevent the delivery of sperm. Illnesses, injuries, chronic health problems, lifestyle choices and other factors can play a role in causing male infertility.

Lifestyle factors affect fertility. As most lifestyle factors can be modified, providing advice and support in making healthy lifestyle changes can promote fertility. The evidence relating to the effects on fertility of caffeine, alcohol consumption and smoking are discussed here. Recent Male Infertility study suggests some new facts which are must read and interesting for anyone trying to get pregnant or start creating family.

A prospective dad must consider his health as important in the journey of parenthood. The biggest cause of infertility in men is abnormal sperm. Sperm can be affected by lifestyle factors such as smoking, drinking alcohol and taking drugs.

1) Caffeine Consumption: Drinking too much coffee can radically reduce a man’s ability to father children, a study has found. Men who drank two or more cups of strong coffee a day had just a one in five chance of becoming fathers through IVF. However, for those who drank less than a cup, the chance of having a child rose to nearly 52%.

2) Alcohol: The studies also showed that men who drink around a pint and a half of beer a night could improve their fertility. The research found that men, who drank at least 22g of alcohol per day, or three units, were more than twice as likely to have children through IVF as those who abstained. Health experts say that moderate amounts of alcohol may reduce stress levels and that in turn help conception. The researchers say no definitive conclusions can be drawn about cause and effect, but young men should be advised that habitual high alcohol intake may affect their reproductive health.

High male caffeine consumption appears to reduce couples’ chance of achieving a clinical pregnancy, while male alcohol consumption appears to enhance their chances.

3) Smoking: Smoking tobacco decreases sperm size and movement and can damage the genetic makeup of sperm cells. It may also have a negative effect on seminal fluid (the fluid that is ejaculated along with sperm). It may take longer for your partner to become pregnant, particularly if you smoke heavily.

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Going to a doctor will help you determine the cause of any fertility problems you may have and give you a chance to talk to the doctor about what you can do to increase your chances of conceiving. Your doctor may refer you to a fertility specialist at a fertility clinic. Couples that are having difficulty getting pregnant may benefit from changing some lifestyle habits and taking help of fertility specialist in ascertaining the real cause of infertility.

Indira Infertility Clinic in Udaipur, has helped countless couples in achieving parenthood. As Indira IVF's Medical Director, Dr. Ajay is a highly skilled fertility specialist committed to patient advocacy with proven expertise in andrology. He brings extensive experience in assisted reproduction treatments like IVF, IUI, ICSI, MESA, TESA to the care of his patients. Apart from this team of doctors at Indira IVf also takes care of other factors contributing to infertility like unexplained infertility, increased age in men and women, lifestyle habits like alcohol, smoking, caffeine, overweight or underweight, sexually transmitted diseases, occupational or environmental factors and stress.

If you are experiencing infertility problems either due to PCOS, endometriosis, varicocele, abnormal sperm count, shape or motility, blocked fallopian tubes or increasing age or secondary infertility you can contact the doctors of Indira IVf at http://www.indiraivf.com/ or at http://www.indiraivf.com/services.html

Read and know more of IVF fertility treatments, IVF & Fertility Success Stories and your options for starting family at http://indiraivf.wordpress.com