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Jul 16
Brazilian researchers say modified butter can treat Alzheimer's
Patients suffering from the first stages of Alzheimer's can benefit from the consumption of butter, enriched with a special fatty acid extracted from milk, Brazilian researchers found.

Tests showed a diet rich in the modified butter increases the activity of an enzyme linked to memory and reduces damage caused by the disease to this function, said the University of Sao Paulo (USP) on its website.

The results of the project, authored by researchers from the Institute of Psychiatry at USP, were featured in the latest edition of the international scientific Journal of Neural Transmission.

According to the researchers, conjugated linoleic acid, an acid extracted from dairy fats, helps the body to increase activity of fosfolipase A2, an enzyme that acts on memory, in the brain, Spanish news agency Efe reported.

The enzyme acts directly on the fats that make up cell membranes, which, among other functions, helps in memory formation.

In healthy patients, these membranes are flexible and are renewed periodically but the carriers of Alzheimer's are rigid, hinder the release of fatty acids, and cannot be replaced at the same rate.

"We saw that the action of this enzyme is altered in Alzheimer's patients, so we began to analyse how we could alter the metabolism of A2 fosfolipase in these patients," explained the head of the Neurosciences Laboratory of the USP, Leda Talib, who coordinated the project.

Experiments with mice, which began five years ago, showed the treatment is effective in patients in early stages of the disease, but researchers are trying to determine whether it can also prevent the disease.

"When the symptoms begin to appear it is because the disease is already established. We do not know at what point it begins, but we will investigate to determine whether the treatment can also be preventive," she said.

Talib added there needs to be more experiments with mice to establish the collateral effects of the modified butter diet, before clinical trials on humans can begin.

"We need to establish whether this diet may cause damage to your health," she concluded.

Jul 15
Kidney stones don't cause osteoporosis in post-menopausal women
Post-menopausal women with kidney or bladder stones are not prone to osteoporosis, but they do have about a 15 percent increased risk of another painful stone, shows research.

Studying the data of approximately 150,000 post-menopausal women, the study found that despite the two conditions being clearly associated in men, the same did not hold true for women.

"We found that, unlike what has been reported in men, a woman having a kidney stone is not a risk factor for osteoporosis. However, having one urinary tract stone does put women at increased risk for a second stone," said Laura D. Carbone, chief of rheumatology section at the Medical College of Georgia at Georgia Regents University.

Carbone said in the study that appeared in the Journal of Bone and Mineral Research. However, women with a stone likely should work with their physician to reduce their increased risk of a subsequent stone.

Having a stone also was known to put people at risk for subsequent stones, but the new study helps clarify the risk. The incidence of urinary tract stones is on the rise generally, particularly in women, with a 70 percent increase in the last 15 years.

One link between the seemingly disparate conditions of stones and weak bones is an excess of calcium in the urine, which tends to be more common in men.

When sodium levels are high, from eating too much processed or fast food, more calcium is eliminated in the urine. Over activity of the parathyroid glands, which regulate levels of calcium in the blood, is associated with both urinary tract stones and fractures of the vertebra in the spine.

Jul 13
Brazilian researchers say modified butter can treat Alzheimer's
Patients suffering from the first stages of Alzheimer's can benefit from the consumption of butter, enriched with a special fatty acid extracted from milk, Brazilian researchers found.

Tests showed a diet rich in the modified butter increases the activity of an enzyme linked to memory and reduces damage caused by the disease to this function, said the University of Sao Paulo (USP) on its website.

The results of the project, authored by researchers from the Institute of Psychiatry at USP, were featured in the latest edition of the international scientific Journal of Neural Transmission.

According to the researchers, conjugated linoleic acid, an acid extracted from dairy fats, helps the body to increase activity of fosfolipase A2, an enzyme that acts on memory, in the brain, Spanish news agency Efe reported.

The enzyme acts directly on the fats that make up cell membranes, which, among other functions, helps in memory formation.

In healthy patients, these membranes are flexible and are renewed periodically but the carriers of Alzheimer's are rigid, hinder the release of fatty acids, and cannot be replaced at the same rate.

"We saw that the action of this enzyme is altered in Alzheimer's patients, so we began to analyse how we could alter the metabolism of A2 fosfolipase in these patients," explained the head of the Neurosciences Laboratory of the USP, Leda Talib, who coordinated the project.

Experiments with mice, which began five years ago, showed the treatment is effective in patients in early stages of the disease, but researchers are trying to determine whether it can also prevent the disease.

"When the symptoms begin to appear it is because the disease is already established. We do not know at what point it begins, but we will investigate to determine whether the treatment can also be preventive," she said.

Talib added there needs to be more experiments with mice to establish the collateral effects of the modified butter diet, before clinical trials on humans can begin.

"We need to establish whether this diet may cause damage to your health," she concluded.

Jul 11
Anxiety-related spectrum disorder identified
Observing higher prevalence of certain physical illnesses among people suffering from panic disorder, US researchers has proposed the existence of a spectrum syndrome comprising a core anxiety disorder and four related domains.

The study published in the Journal of Neuropsychiatry and Clinical Neurosciences points to a link between mental and physical health.

When mental and physical illnesses co-occur, patients' accounts of physical illness are sometimes arbitrarily discredited or dismissed by physicians. The naming of the new disorder may help many patients receive proper diagnosis.

"Patients who have certain somatic disorders - illnesses for which there is no detectable medical cause and which physicians may consider to be imagined by the patient - may instead have a genetic propensity to develop a series of real, related illnesses," said one of the researchers Jeremy Coplan, professor of psychiatry at SUNY Downstate Medical Centre in the US.

"Panic disorder itself may be a predictor for a number of physical conditions previously considered unrelated to mental conditions, and for which there may be no or few biological markers," Coplan said.

The researchers found correlation between panic disorder, bipolar disorder, and physical illness, with significantly higher prevalence of certain physical illnesses among patients with panic disorder when compared to the general population.

To describe the new spectrum disorder, the researchers have coined the term ALPIM, where "A" stands for anxiety disorder (mostly panic disorder); "L" for ligamentous laxity (joint hypermobility syndrome, scoliosis, double-jointedness, mitral valve prolapse, easy bruising); "Pa for pain (fibromyalgia, migraine and chronic daily headache, irritable bowel syndrome, prostatitis/cystitis); "I" for immune disorders (hypothyroidism, asthma, nasal allergies, chronic fatigue syndrome); and "M" for mood disorders.

Two thirds of patients in the study with mood disorder had diagnosable bipolar disorder and most of those patients had lost response to antidepressants.

"Our argument is that delineations in medicine can be arbitrary and that some disorders that are viewed as multiple disparate and independent conditions may best be viewed as a single spectrum disorder with a common genetic etiology."

Jul 09
Eating fruits, veggies can lower risk of heart disease: Study
High vitamin C concentrations in the blood from the intake of fruit and vegetables are associated with a reduced risk of cardiovascular disease and early death, a new large-scale study has found.

Researchers from the University of Copenhagen and Herlev and Gentofte Hospital in Denmark studied data from 100,000 Danes and their intake of fruit and vegetables as well as their DNA.

"We can see that those with the highest intake of fruit and vegetables have a 15 per cent lower risk of developing cardiovascular disease and a 20 per cent lower risk of early death compared with those who very rarely eat fruit and vegetables," said Camilla Kobylecki, a medical doctor and PhD student at the Department of Clinical Biochemistry, Herlev and Gentofte Hospital.

"At the same time, we can see that the reduced risk is related to high vitamin C concentrations in the blood from the fruit and vegetables," Kobylecki said.

Vitamin C is a potent antioxidant which protects cells and biological molecules from the damage which causes many diseases, including cardiovascular disease.

The human body is not able to produce vitamin C, which means that we must get the vitamin from our diet.

"Eating a lot of fruit and vegetables is a natural way of increasing vitamin C blood levels, which in the long term may contribute to reducing the risk of cardiovascular disease and early death," said Borge Nordestgaard, a clinical professor at the Faculty of Health and Medical Sciences, University of Copenhagen, and a consultant at Herlev and Gentofte Hospital.

"You can get vitamin C supplements, but it is a good idea to get your vitamin C by eating a healthy diet, which will at the same time help you to develop a healthier lifestyle in the long term, for the general benefit of your health," said Nordestgaard.

The study has just been published in the American Journal of Clinical Nutrition.

Jul 04
Being a vegan helps lose weight: Study
If you are looking for a size zero figure, then following a vegan diet that includes no animal products could offer better results than other weight-loss plans, says a study.

"Vegetarian diets are more effective than non-vegetarian diets for weight loss," said researcher Ru-Yi Huang of E-Da Hospital in Taiwan.

The study reviewed the results of twelve diet trials, involving 1,151 dieters who followed a specific eating regime for between nine and 74 weeks.

Overall, individuals assigned to the vegetarian diet groups lost significantly more weight (around 2.02 kg) than dieters who ate meat and other animal products.

Vegetarians who followed a vegan diet lost even more weight. Comparatively, they lost around 2.52 kg more than non-vegetarian dieters. Vegetarians who consumed dairy products and eggs lost around 1.48 kg more than those on a non-vegetarian diet.

According to Huang, the abundant intake of whole grains, fruits and vegetables might play a role in the favourable results seen in vegetarian diets.

Whole-grain products and vegetables generally have low glycaemic index values and do not cause blood sugar levels to spike. Fruits are rich in fiber, anti-oxidants, minerals and protective chemicals that naturally occur in plants.

Whole-grain products contain soluble fiber. Such so-called good fiber helps to delay the speed by which food leaves the stomach and ensures good digestion.

The researchers found that people following vegetarian diets that prescribe a lower than normal intake of calories (so-called energy restriction) also shed more kilograms than those without any such limitations being placed on their eating habits.

The findings appeared in the Journal of General Internal Medicine.

Jul 03
'Too much' available food to be blamed for obesity crisis
It's the abundance of food that's been causing an obesity epidemic, claims a new research.

Of the 56 out of 69 countries surveyed, average body weight had increased as a result of available food supply, with only countries hit by famine, natural disasters or civil war not in the list.

Researchers from the University of Auckland, New Zealand, and the National Institutes of Health in the US, said that it was major factor in the growing obesity epidemic throughout the world, the Telegraph reported.

In Britian, researchers found that each person had 3428 calories available to them each day, which was 70 per cent more than required by women, and 37 per cent more than men's recommended daily intake.

It has risen by 212 calories since 1993.

Lead author Stefanie Vandevijvere said their study showed that oversupply of available calories possibly leads to overconsumption of those calories, resulting in the weight gain seen in most countries.

Scientists also found that the increases were far in excess of what was required to explain the weight gain experienced by each country, suggesting that food waste had also increased substantially.

Weight gain has been stated as a risk factor for many major health problems, like diabetes, heart disease, stroke and even some cancers.

The study highlights the need for the governments to implement policies to make food healthier.

Dr Francesco Branca, director of the Department of Nutrition for Health and Development at WHO, countries need to look at how they guide the food system, and work across sectors including agriculture, the food production, distribution and retail industries, health, social welfare and education.

The study is published in the Bulletin of the World Health Organisation.

Jul 02
Eat nuts to keep obesity at bay
A new study has linked tree nuts to lower body weight and risk of obesity.

Researchers compared risk factors for heart disease and metabolic syndrome of tree nut consumers versus those who did not consume tree nuts. Tree nut (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) consumption was associated with lower body mass index, systolic blood pressure, insulin resistance and higher levels of high-density lipoprotein-cholesterol (good cholesterol).

In addition, tree nut consumers were 25 percent less likely to be obese and 21 percent less likely to have an elevated waist circumference than those who did not consume tree nuts.

Research has shown that nuts can help reduce the risk of cardiovascular disease and metabolic syndrome (MetS). The latter is a cluster of risk factors for cardiovascular disease and type 2 diabetes and includes elevated blood lipids, blood pressure, blood sugar, insulin resistance and abdominal obesity.

Maureen Ternus, Executive Director of the International Tree Nut Council Nutrition Research & Education Foundation (INC NREF), said that just 1.5 ounces of nuts per day (about 1/3 cup) can give you many of the important vitamins, minerals and energy you need throughout the day.

The study is published in Nutrition Journal.

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