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Feb 15
'Mental wellness gaining credence'
CHENNAI: There is a growing understanding in medical science of the role our brains play, in determining what are predominantly emotional symptoms, Professor Fred Ovsiew, NorthWestern University, Chicago, USA, has said.

Delivering the 30th TS Srinivasan Endowment Oration on 'Hysteria! The Road Less Travelled Between The Brain and Mind' here on Saturday, Prof Fred Ovsiew said, "The reintegration of people into society, as they recover from illness, therefore requires as imperative, the restoration of both their mental capital and mental well being." He also said hysteria exemplifies the importance of the mind in modern medicine.

It may well have origins in the brain, which affects mental capital and well being.

However early diagnosis and intervention is key to a potential cure, he added.

Dr E S Krishnamoorthy, honorary secretary, TS Srinivasan Chair in Clinical Neurosciences and Health Policy and Voluntary Health Services- Multi-specialty Hospital and Research Institute, said, "From a clinical practice perspective also, the importance of mental health, wellness and health related quality of life, as outcome indicators of both physical and mental disorders is being widely accepted."

Feb 13
Will Bill Clinton slow down after heart procedure?
Right until he was wheeled into an operating room for a heart procedure, Bill Clinton was on the phone, talking about Haiti earthquake relief. An aide finally took the phone away from him.

On Friday, the 63-year-old former president seemed to have returned to multitasking, just a day after having a clogged artery reopened and two stents inserted into his chest.

"I feel great. ... I even did a couple miles on the treadmill today," Clinton said, speaking to reporters in a leather jacket from the driveway outside his home. He said doctors advised him "not to jog but walk. Not to walk fast up steep hills for a week."

Aides said Clinton's second heart procedure in five years seemed unlikely to slow down his brutal work schedule, which included two trips to Haiti, stumping for Senate candidate Martha Coakley and attending an economic summit in Switzerland - all in just over a month.

"He's working as hard as he's ever worked. He's done it for 63 years and will do it for the next 63 years. He's never going to stop," said Paul Begala, a Democratic strategist who helped guide Clinton's first presidential bid in 1992.

But some other advisers said Clinton's brief hospitalization was a reminder that his health has become more fragile. They worried that he's running too hard.

"He's got to slow down," Pennsylvania Gov. Ed Rendell said on MSNBC Friday. "He's got to slow down to a good, human schedule. He's had a superhuman schedule for a long while, and he's got to cut back. There's no question about it."

Advisers said the Haiti earthquake-relief effort have been Clinton's main focus, and he appeared to return to that cause on Friday.

Through his foundation, Clinton put out a statement marking the one-month anniversary of the quake and urging people to donate. He said nothing about his health.

The Clinton Foundation's Haiti fund has given $7 million to relief organizations in the aftermath of the quake that killed more than 200,000 people.

Clinton said Friday that he had been working long hours on the Haiti relief effort, including taking three overnight flights in a week. He said his first symptoms were about four days ago, when he felt "just a little bit of tingling, not pain."

Clinton has been doing more than most people do in a day or a month: On Jan. 7, he met with President Obama at the White House. Five days later, he attended the funeral of Vice President Joe Biden's mother in Delaware.

On Jan. 15, he campaigned for Coakley in the race for the late Sen. Ted Kennedy's seat in Massachusetts. Three days later, he toured a destroyed hospital in Haiti.

On Jan. 28, he made an appeal for Haiti aid at the World Economic Forum in Davos, Switzerland, and was back in Haiti on Feb. 5.

"He's just constitutionally unable to say no to a good cause, to say no to a good candidate," Rendell said.

Terry McAuliffe, former Democratic National Committee chairman and a close friend of the Clintons, told CBS' "The Early Show" that it was probably time for Clinton to slow down. But "you can't change him."

"If I know President Clinton, he'll be on the phone ... calling people asking for more help for Haiti and where he can get pickup trucks so they can deliver food or generators. If I know Bill Clinton, he'll be raring to go in about 35 minutes," McAuliffe said.

Clinton consulted with his cardiologist Thursday after suffering discomfort in his chest for several days. He had the procedure at New York Presbyterian Hospital, the same place where he underwent quadruple bypass surgery in 2004.

Shortly before 8 a.m. Friday, three black SUVs with tinted windows arrived in Chappaqua, a wealthy suburb about 35 miles north of Manhattan.

Clinton returned home with his wife, Secretary of State Hillary Rodham Clinton, advisers said.

A couple of hours later, C.J. Williams, a second-grader from New Fairfield, Conn., arrived at the cul-de-sac carrying a get-well card and a red heart-shaped box filled with Skittles.

The sandy-haired boy said he wrote on the card, "Happy Valentine's Day. I hope you feel better, and here's a little heart to make your big heart feel better."

An officer told C.J. and his father that they would have to mail the items.

Aides said Mrs. Clinton plans to leave Saturday for the Persian Gulf. State Department spokesman P.J. Crowley said the secretary of state is "confident enough that she can go on this trip as originally planned," especially after the former president's speedy return home.

Clinton's cardiologist said he expected Clinton to go back to work Monday.

Rep. Anthony Weiner, a New York Democrat who visited Clinton in the hospital, said returning to a full schedule may help his health more than it hurts him.

"Bill Clinton operating at quarter-speed is twice what most people do at full-speed," Weiner said. "His work on behalf of Haiti and the Clinton Global Initiative, I think, keeps him young, much more than it wears him out."

Clinton said taking care of his health has forced him to sleep more. But he said it has not slowed his work schedule.

"It's what I should do. That's what my life is for," he said. "I've been given a good mind, a strong body ... It would be wrong for me not to work."

Feb 13
Doctor on train starts with Duronto
Doctors on board long-distance trains are all set to make a debut with the Railways deciding to depute one General Duty Medical Officer and one paramedical staff in all Duronto (end-to-end nonstop) trains as a pilot project for a year.

The medical services will come free of cost. Nine pairs of Duronto trains are currently operational.

Deciding to earmark two berths in an AC-2 compartment for the doctor and the attendant, the Railways have authorised the zonal railways to purchase equipment like ECG, ophthalmoscope, glucometer and treatment equipment like defibrillators, portable suction apparatus, oxygen cylinders and nebulizers.

The mechanical and electrical departments have been told to make necessary modifications in coaches to provide oxygen cylinder holders, drip set holders, and extra lighting for patient management and extra plug points for resuscitation equipment.

Once a passenger is examined, the medical team will be allowed to move the person to a designated patient-care sick bay on the train.

In case the doctor decides that that passenger needs to be detrained, the train superintendent will stop the train at the next station that has medical facilities.

The station manager will be responsible for transferring a patient from the station to the nearest medical centre.

Feb 12
Baked rhubarb could help battle cancer
Rhubarb could hold the key to battling cancer, believe scientists at Sheffield Hallam University.


In the study, scientists found that when baked for 20 minutes, the plant released high levels of cancer-killing chemicals called polyphenols, reports The Daily Express.


Rhubarb has been used for centuries in Chinese medicine. Ground roots of the plant are believed to help shrink tumours.

Dr Nikki Jordan-Mahy, of the university's Biomedical Research Centre, said: "Our research has shown that British rhubarb is a potential source of pharmacological agents that may be used to develop new anti-cancer drugs."

The research team used rhubarb grown indoors in candlelight to produce a darker red stem, as it is higher in polyphenols than paler varieties. The team plans to carry out lab tests to see if rhubarb polyphenols can kill a variety of cancer cells taken from patients with leukaemia.

A study published in the journal Food Chemistry shows rhubarb is at its anti-cancer best after 20 minutes in the oven. (ANI)

Feb 11
'Artificial pancreas' for diabetics
Scientists have used an artificial pancreas system of pumps and monitors to improve blood sugar control in diabetes patients in the first study to show the new device works better than conventional treatment.

Medical device makers have been working for years to develop a so-called artificial pancreas to deliver insulin to patients with type 1 diabetes, an autoimmune disease in which the body destroys its own ability to make insulin.

The bodies of type 1 diabetes sufferers become unable to properly break down sugar and if untreated, blood vessels and nerves are destroyed, organs fail and patients die. These devices could transform the management of type 1 diabetes, but it is likely to be a gradual process.

Researchers tested the device on 17 children with type 1 diabetes during a series of nights in hospital and found it kept their blood sugar levels within the important normal range for 60 percent of the time. The new system, which involves patients wearing a matchbox-sized monitor and a similar-sized pump with a tube to deliver insulin into the body, also halved the amount of time blood sugar dropped to worrying or dangerous levels.

The above results are an important stepping stone toward bringing an artificial pancreas to the commercial market, but predicted several years yet of refinement before it could be used day and night by patients in normal life.

The ultimate goal is to create a device that can check patients' blood day and night, during and between meals, and deliver insulin as required. The study found that the device performed better than a conventional pump, which delivers insulin at pre-set rates and which kept blood sugar levels around normal for 40 percent of the time compared with 60 percent for the artificial pancreas.

The above findings are particularly encouraging because the study included nights when the children went to bed after eating a large evening meal or having done exercise - both of which can affect blood sugar levels.

Feb 09
Family meals cut childhood obesity risks
Childhood obesity is on the rise but routine activities like eating dinner together, limiting hours of watching television and getting adequate sleep can lower down the risk of childhood obesity, according to a new study published in the journal Pediatrics.

The All India Institute of Medical Sciences (AIIMS), New Delhi conducted a survey on children aged between 14 and 18 and reported that of the 2000 children studied, 17 percent were obese or overweight. Obesity in children is usually a result of the sedentary lifestyle, improper food habits and lack of physical activity. This may result in the child growing up to become an obese adult.

Obesity is one of the leading causes of many disorders like diabetes, cardiovascular disease, high blood pressure and sleep disorders.

The researchers from Ohio State University and Temple University examined the link between childhood obesity among preschool children with three household activities-- limited hours of television, adequate sleep hours and having dinner together with family members.

It was found that four year old children who are involved in all these activities were almost 40 percent lower risk of having obesity compared to children who were not involved in any of these.

Ensuring regular routines of having meals together, going to sleep at a definite time and limiting the TV time can reduce risks of obesity in children. Also involvement in physical activity and to eat healthy food should also be initiated by the family members.

Feb 09
Test-tube boys may inherit fertility problems
DOCTORS have uncovered the first evidence that fathers of test-tube babies may be passing on their infertility to their sons.

A new study has found that boys conceived through IVF treatment involving a single sperm being directly injected into a female egg often inherit shorter fingers, a trait known to be associated with infertility.

The results raise the prospect of a new and growing generation who may be less likely to have children of their own.

There are now an estimated 1m children across Europe born through IVF treatment.

Almost one in 50 British babies is conceived artificially and nearly half the couples having treatment go through a procedure known as ICSI (intracytoplasmic sperm injection).

The technique bypasses the normal competition where only the healthiest sperm cell is able to reach the female egg and fertilise it.

Alastair Sutcliffe, a paediatrician at the Institute of Child Health in London, led the Anglo-German study which compared 211 six-year-olds conceived through ICSI with 195 naturally conceived children of the same age.

The ICSI group were similar heights to the naturally conceived group, but the boys had significantly shorter fingers.

It is known that men with low sperm counts often have ring fingers the same length as their index finger, whereas fertile men are more likely to have a ring finger which is relatively longer than their index finger.

The effect is reversed in women, where the most fertile are likely to have index fingers significantly longer than their ring fingers.

Sutcliffe;s findings appeared recently in the journal Reproductive Biomedicine Online.

"This is the first study of this kind on these children," Sutcliffe said.

"We don't yet know the implication of the findings because the children are very young, but we need to inform people [about the possible risks of the ICSI procedure]."

Scientists have long suspected that the test-tube baby boom would bring its own problems. Infertility treatment began as a commercial operation only in the 1990s. The first ICSI baby was born in 1992 and there are now about 3,700 such births a year in Britain.

Finger length is known to be set within the first 14 weeks of pregnancy and is linked to testosterone exposure which is, in turn, governed by a specific group of genes.

"This [research] is telling us that we should only use ICSI when it is absolutely necessary," said John Manning, an evolutionary biologist at Southampton University who has examined the link between finger length and fertility and who is one of the authors of the latest study.

"We know the extraordinary depression and pain that childlessness can cause and we have a responsibility to ensure that the focus on the wellbeing of the children born as a result of these techniques is as high as it can be."

Feb 08
Kidney function and bone loss
Even a slight loss of kidney function is associated with increased loss of bone mineral density and greater risk of disabling fractures that can lead to premature death.

The relationship between kidney function and bone loss is unclear. To look into this association, researchers followed Canadians adults - 191 men and 444 women, aged 50 years and older, for five years. They assessed participants' kidney function and bone mineral density at the start and end of the study.

It was found that people with impaired kidney function lost bone mineral density faster than those with healthy kidneys. For example, study participants with the worst kidney function had a 9.3 percent greater decrease in lower spine bone mineral density over the five years than those with healthy kidneys.

The new findings highlight the potential impact of early identification of kidney disease in preventing complications that can cause disability and premature death.

Feb 08
New drug hope for osteoporosis cure
A pill that blocks production of a natural chemical in the gut could potentially cure the common bone thinning disease osteoporosis, say scientists.

The drug prevents the synthesis of serotonin, best known for its functions in the brain.

It halted osteoporosis in mice and rats, and may be similarly effective in humans, researchers believe.

In the brain, serotonin assists the transmission of messages between nerve cells and has a big impact on mood.

But 95% of the body's serotonin is found in the gut, where its major function is to inhibit bone formation, said the researchers.

By shutting off intestinal serotonin production, the scientists prevented osteoporosis in post-menopausal female mice.

In humans, the menopause is known to increase the risk of the disease dramatically.

The researchers found that an experimental drug called LP533401, which blocks serotonin production in the gut, had a major impact on osteoporosis.

They included the drug in the animals' diets at small doses once a day for up to six weeks.

The results, published in the journal Nature Medicine, showed that LP533401 prevented osteoporosis developing. When the disease was already present, it could be fully cured.

Feb 06
Physicists Kill Cancer With 'Nanobubbles'
Nanoparticles, scientists at Rice University have discovered a new technique for singling out individual diseased cells and destroying them with tiny explosions. The scientists used lasers to make "nanobubbles" by zapping gold nanoparticles inside cells. In tests on cancer cells, they found they could tune the lasers to create either small, bright bubbles that were visible but harmless or large bubbles that burst the cells.

"Single-cell targeting is one of the most touted advantages of nanomedicine, and our approach delivers on that promise with a localized effect inside an individual cell," said Rice physicist Dmitri Lapotko, the lead researcher on the project. "The idea is to spot and treat unhealthy cells early, before a disease progresses to the point of making people extremely ill."

The research is available online in the journal Nanotechnology.

Nanobubbles are created when gold nanoparticles are struck by short laser pulses. The short-lived bubbles are very bright and can be made smaller or larger by varying the power of the laser. Because they are visible under a microscope, nanobubbles can be used to either diagnose sick cells or to track the explosions that are destroying them.

In laboratory studies published last year, Lapotko and colleagues at the Laboratory for Laser Cytotechnologies at the A.V. Lykov Heat and Mass Transfer Institute in Minsk, Belarus, applied nanobubbles to arterial plaque. They found that they could blast right through the deposits that block arteries.

"The bubbles work like a jackhammer," Lapotko said.

In the current study, Lapotko and Rice colleague Jason Hafner, associate professor of physics and astronomy and of chemistry, tested the approach on leukemia cells and cells from head and neck cancers. They attached antibodies to the nanoparticles so they would target only the cancer cells, and they found the technique was effective at locating and killing the cancer cells.

Lapotko said the nanobubble technology could be used for "theranostics," a single process that combines diagnosis and therapy. In addition, because the cell-bursting nanobubbles also show up on microscopes in real time, Lapotko said the technique can be use for post-therapeutic assessment, or what physicians often refer to as "guidance."

Hafner said, "The mechanical and optical properties of the bubbles offer unique advantages in localizing the biomedical applications to the individual cell level, or perhaps even to work within cells."

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