World's first medical networking and resource portal

News & Highlights
Please make use of the search function to browse preferred content
Medical News & Updates
Apr 16
Sperm may deliver stress too!
Your dad did not just pass his qualities via genes in you. He may have actually passed some stress too!

A research reveals that stress alters the expression of small RNAs in sperms and leads to depressive behaviours in later generations.

In lab research, scientists found that stress in early life altered the production of small RNAs, called microRNAs, in the sperm of mice.

The mice showed depressive behaviours that persisted in their progeny which also show glitches in metabolism.

"Dad is having a much larger role than just delivering his genome," said Isabelle Mansuy, a neuroscientist at University of Zurich, Switzerland.

Mansuy and her colleagues periodically separated mother mice from their young pups and exposed the mothers to stressful situations - either by placing them in cold water or physically restraining them.

These separations occurred every day but at erratic times, so that the mothers could not comfort their pups with extra cuddling before separation.

When raised this way, male offspring showed depressive behaviours and tended to underestimate risk, the study found.

Their sperm also showed abnormally high expression of five microRNAs.

One of these, miR-375, has been linked to stress and regulation of metabolism.

Mansuy and her team are now looking into whether similar microRNA biomarkers occur in people exposed to traumatic events - or in their children.

"If some are altered persistently in blood, then they could be used as markers for susceptibility to stress or for developing psychiatric disorders," she noted in the study published in the journal Nature Neuroscience.

Apr 16
Low glucose levels may make you cranky and lash out at your spouse
A new research suggests that people who generally have lower levels of glucose are more likely to lash out aggressively at their spouses.

According to Brad Bushman, the lead author of the study conducted at The Ohio State University, "Hunger caused by low levels of blood glucose may play a role in marital arguments, confrontations and possibly even some domestic violence".

The research involved 107 married couples. The study started with the couples completing a relationship satisfaction measure, which asked each spouse how much they agreed with statements like "I feel satisfied with our relationship".

During a 21-day study, researchers found that levels of blood glucose in married people, measured each night, predicted how angry they would be with their spouse that evening.

At the end of 21 days, people who had generally lower levels of glucose were willing to blast their spouses with unpleasant noises at a higher volume and for a longer time than those who had higher glucose levels.

Even those who reported they had good relationships with their spouses were more likely to express anger if their blood glucose levels were lower.

Blood glucose levels can be brought up most quickly by eating carbohydrates or sugary foods.

The study has appeared online in the journal Proceedings of the National Academy of Sciences.

Apr 15
Green space keeps you from feeling blue
The more green space a neighborhood has, the happier the people are, a new study has revealed.

Dr. Kristen Malecki, assistant professor of population health sciences at the University of Wisconsin School of Medicine and Public Health said that the results are striking across neighborhoods of Wisconsin, from the North Woods to the cities, and higher levels of green space were associated with lower symptoms of anxiety, depression and stress.

The study, which combines mental-health data from the Survey of the Health of Wisconsin (SHOW) and Landsat 5 satellite data from July 2009 that analyzed how much vegetation was present in each of the SHOW census blocks.

About 2,500 Wisconsin residents from 229 neighborhoods answered an assessment that asked them to rate their symptoms of depression, anxiety and stress, and it was found that across all strata of society, people who lived in a neighborhood with less than 10 percent tree canopy were much more likely to report symptoms of depression, stress and anxiety.

The greening of neighborhoods could be a simple solution to reducing stress, and going outside will make one feel better, said Malecki.

The study was published recently in the International Journal of Environmental Research and Public Health.

Apr 15
New laser scanner can detect arthritis before symptoms start
British scientists are developing a new laser scanner which could revolutionise arthritis treatment. This device can detect arthritis even before the symptoms start.

The new scanner could help start arthritis treatment by spotting signs of the crippling disease before it has done painful and irreversible damage to cartilage in the joints.

Professor Allen Goodship, of University College London said that the research is at an early stage but the results are promising and possibly in the future, the technique, called Spatially Offset Raman Spectroscopy, could be effective as a screening tool.

Apr 14
Confirmed: Smoking ruins your taste buds
Well there are umpteen number of reasons why you shouldn't smoke. Adding to that, there is another one now which says that smoking totally ruins your taste buds. Your taste buds being affected, you won't be able to completely enjoy the food/drinks that you really like.

It happens so that smokers' ability to taste is impaired by toxic chemicals found in tobacco, even after they have quit smoking. So they do not enjoy their coffee despite the strong, bitter taste of caffeine which can be easily detected.

Scientists tested how well 451 volunteers could recognise the four basic flavours of sweet, sour, bitter and salty, as well as the intensity of each taste as a part of this study.

Researchers found that whether the volunteers smoked or not did not affect whether they could recognise salty, sweet or sour tastes -- but it did have an effect where the bitter taste of caffeine was concerned.

One in five smokers and one in four ex-smokers could not correctly recognise the taste.However, 13 percent of non-smokers also failed the taste test.

According to the researchers ,the build-up of tobacco in the body could stop taste buds renewing themselves and so harm a person's ability to recognise certain tastes, even after they have stopped smoking.

Apr 14
189,000 kids get anti-polio vaccine in Syria
A total of 189,000 children, aged below five, have been vaccinated against polio for the past week in the the central province of Homs, as part of a national government campaign in the war-torn country, state media reported.

The national vaccination campaign, the fifth one since last year, started Sunday. It has provided children under the age of five with free vaccines in 50 towns of Homs and some of its hotspot suburbs, Xinhua quoted citing data from the health department of Homs.

The World Health Organisation (WHO) said recently that the recent polio outbreak in Syria is the first since 1999.

Preliminary evidence indicates that the poliovirus is of Pakistani origin and is similar to the strain detected in Egypt, the West Bank and Gaza Strip over the last 12 months.

Polio is a highly infectious disease caused by a virus that invades the nervous system. It can cause complete paralysis in a matter of hours. The virus enters the body through the mouth and multiplies in the intestine.

According to WHO, the health situation in Syria has been deteriorating due to shortage of medicines and medical workers, destruction of health facilities and difficult access to health care.

Apr 11
Consuming high-fat diet increases breast cancer risk
A new study has revealed that consuming a high-fat diet is associated with increased risk of certain types of breast cancer.

According to the researchers, high total and saturated fat intake were associated with greater risk of estrogen receptor- and progesterone receptor-positive (ER+PR+) breast cancer (BC), and human epidermal growth factor 2 receptor-negative (HER2-) disease.

Published data from epidemiological and case-control studies on the association between high fat intake and BC risk have been conflicting, which may be attributable to difficulties obtaining accurate information on fat intake and because of limited heterogeneity of intake within a specific geographic area from which the study cohorts live.

Furthermore, BC is now classified clinically into subtypes by ER, PR, and HER2 expression status and each subtype has its own prognosis and set of risk factors, which may also contribute to the inconsistencies in the published reports on this relationship.

Sabina Sieri, Ph.D., from the Epidemiology and Prevention Unit of the Department of Preventive and Predictive Medicine at Fondazione IRCCS Istituto Nazionale Dei Tumori in Milan Italy, and colleagues prospectively analyzed data from 10,062 BC patients from the EPIC study with 11.5 years of follow-up.

The authors report high total and saturated fat intake were associated with greater risk of ER+PR+ BC. High saturated fat intake was also associated with greater risk of HER2- disease.

The authors conclude, "a high-fat diet increases BC risk and, most conspicuously, that high saturated fat intake increases risk of receptor-positive disease, suggesting saturated fat involvement in the etiology of receptor-positive BC."

The study is published in the Journal of the National Cancer Institute.

Apr 11
Merck's hepatitis C drugs show 98% cure rate in trial
Offering new hopes to millions of people infected with Hepatitis C, a two-drug combination by Merck & Co to treat the infectious liver disease has showed a cure rate of 98% in a mid-stage trial.

The results of the 12-week study called C-Worthy were presented on Thursday at the annual meeting of the European Association for the Study of the Liver (EASL) in London.

In the study, 44 patients were treated with MK-5172 and MK-8742 once a day for 12 weeks, where 43 of them achieved sustained virologic response (SVR), which is considered cured or a 98% cure.

Merck also said that when the two drugs were given to some patients along with ribavirin, an older virus-fighting drug, it showed a 94% cure rate.

Gilead Sciences Inc, AbbVie and Bristol-Myers Squibb Co are also developing a new generation of all-oral hepatitis C treatments that in previous trials have demonstrated cure rates in excess of 90%.

The drug maker said after analysing the results of the study, it has begun to initiate a phase 3 trial.

Apr 08
New drug may help prevent advanced breast cancer from progressing
It could be a groundbreaking treatment option for women with Breast cancer.Scientists have revealed that a new drug can help prevent advanced breast cancer from progressing.

The drug, palbociclib could cut in half the risk that the cancer would worsen.

The principal investigator Dr. Richard S. Finn, remarked that the magnitude of benefit they are seeing is not something commonly seen in cancer medicine studies.

The drug, palbociclib, developed by pharmaceutical giant, Pfizer, appears to prolong survival, though not by a statistically significant amount.

Finn added that a statistically significant survival benefit should not have been expected at this point because only 61 of the 165 patients in the trial had died.

Apr 08
Drink green tea to boost your brain power
Researchers have reporting first evidence that green tea extract enhances the cognitive functions, in particular the working memory.

In the new study, the researcher teams of Prof. Christoph Beglinger from the University Hospital of Basel and Prof. Stefan Borgwardt from the Psychiatric University Clinics found that green tea extract increases the brain's effective connectivity, meaning the causal influence that one brain area exerts over another.

This effect on connectivity also led to improvement in actual cognitive performance: Subjects tested significantly better for working memory tasks after the admission of green tea extract.

For the study healthy male volunteers received a soft drink containing several grams of green tea extract before they solved working memory tasks. The scientists then analyzed how this affected the brain activity of the men using magnetic resonance imaging (MRI).

The MRI showed increased connectivity between the parietal and the frontal cortex of the brain. These neuronal findings correlated positively with improvement in task performance of the participants. "Our findings suggest that green tea might increase the short-term synaptic plasticity of the brain," says Borgwardt.

The study has been published in the journal Psychopharmacology.

Browse Archive