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Jul 17
Drinking too much tea can cause bone problems
A new research by Medical College of Georgia has shown that black tea contains higher concentrations of fluoride than previously thought.

'The additional fluoride from drinking two to four cups of tea a day won't harm anyone; it's the very heavy tea drinkers who could get in trouble,' said Dr. Gary Whitford, Regents Professor of oral biology in the School of Dentistry.

Most published reports show 1 to 5 milligrams of fluoride per litre of black tea, but a new study shows that number could be as high as 9 milligrams.

Fluoride is known to help prevent dental cavities, but long-term ingestion of excessive amounts could cause bone problems.

Whitford discovered that the fluoride concentration in black tea had long been underestimated when he began analysing data from four patients with advanced skeletal fluorosis, a disease caused by excessive fluoride consumption and characterized by joint and bone pain and damage.

'When we tested the patients' tea brands using a traditional method, we found the fluoride concentrations to be very low, so we wondered if that method was detecting all of the fluoride,' Whitford said, noting that the tea plant, Camellia sinensis, creates a quandary when measuring fluoride.

Unique among other plants, it accumulates huge concentrations of fluoride and aluminium in its leaves. When the leaves are brewed for tea, some of the minerals leach into the beverage.

Jul 15
India's 1st nasal spray swine flu vaccine launched
Finally, India gets its first prick-free vaccine to fight the deadly H1N1 strain.

Pune's Serum Institute of India (SII) launched its much awaited "cheaper" and "painless" solution against the virus -- a ready-to-sniff intra-nasal vaccine, Nasovac, on Wednesday across the country.

At the launch, Adar Poonawalla, owner and executive director, Serum Institute of India Ltd. stated, "The public's fear at the height of the pandemic last year was a challenge for India's healthcare sector.

"Right from the time we started work on the vaccine, we were clear that apart from developing indigenous capability for tackling pandemics, we wanted to provide a painless prevention option for the masses.

"We now have capabilities, in collaboration with global healthcare agencies, to respond with affordable preventive vaccines for pandemic healthcare emergencies anywhere around the world."

A little about Nasovac
Nasovac, meant for the H1N1 pandemic strain, is a nasal spray in powder form, which has to be reconstituted by adding water.

A single dose of 0.5ml of the vaccine is delivered directly to the nasal cavity through a device fitted at the top of the syringe.

A quick spray in each nostril and the body develops antibodies to protect against the deadly virus for a period of over a year or even more.

According to experts, the nasal spray may prove to be effective as it takes the same respiratory route as the H1N1 virus. It has the efficiency to fight H1N1 infection even if small changes occur in the virus.

After vaccination, some negligible or very mild reactions may be experienced for two to three days.

Safety and efficacy assessed
The safety and efficacy of the vaccine was assessed through clinical trials on more than 300 human subjects in the country.

The vaccine has been approved by the Drug Controller of India (DCGI) and can be safely administered to any individual above three years.

However, SII is not recommending the vaccine for pregnant
women and lactating mothers.

Dr Cyrus Poonawalla, chairman, SII stated, "Our recommendation is that it (Nasovac) should not be administered to pregnant and lactating women, besides children below three years.

"But the medical fraternity says this decision should be left to them. They think that if the women are in a high-risk area, they should be vaccinated. So we have no objection, but it is better that if these vaccines are not given to them."

Economically priced
In order to increase its commercial use among the masses, Nasovac is economically priced.

SII has set a sale target of 20-25 million doses in first year.

In addition, SII donated vaccines worth Rs 10 crore to various hospitals, NGOs, and the underprivileged.

Mansoor Ahmed, marketing director, SII, said, "The product will be available across the country in the next few days. It is priced at Rs. 158 per dose and available in the 5-vial pack for Rs. 790.

"As of now, we have the capacity to make 50 million doses. But this can be scaled up in the coming months to 150 million or even 200 million doses if needed. As of now, we are only concentrating on the Indian market and will address the export market later."

Jul 15
New phase in global AIDS battle
AIDS experts gather in Vienna on Sunday for a six-day rally on the new options emerging in a war which after nearly three turbulent decades is entering a stable, promising phase.

Expected to draw more than 20,000 researchers, policymakers and grassroots workers, the International AIDS Conference is the 18th since acquired immune deficiency syndrome came to light in 1981.

For almost all this time, the conferences have been the theatre for frustration and sometimes anger. Doctors would reel off the latest setbacks in the quest to treat and prevent the AIDS virus, while activists pounded the drum for money and action by Big Pharma.

Today, though, the mood is brighter than ever. Indeed, many AIDS warriors are talking cautiously of a foe that is on the way to being contained and one day will be rolled back.

"One day, we will have to turn our minds on how to wipe out the virus," Jean-Francois Delfraissy, director of France's National Agency for AIDS Research (ANRS), said in an interview.

The optimism comes from the success of antiretroviral drugs, the "cocktail" of drugs that, like a boot pressed firmly on the throat of a killer, keeps HIV suppressed.

For millions, this medication has transformed the human immunodeficiency virus (HIV) from a death sentence to a chronic but manageable disease.

Even better, antiretrovirals are also emerging as a policy tool for prevention. Lowering viral levels to below perceptible levels massively reduces the risk of handing on the pathogen between sex partners or from a pregnant mother to her child.

There is also hugely encouraging news about male circumcision for preventing the spread of HIV to men, and even a few glimmers of hope from the lab, where scientists are toiling for a vaccine and virus-thwarting microbicide gel.

"We really are at an important crossroads," Gottfried Hirnschall, new director of HIV/AIDS at the UN's World Health Organisation (WHO), said in an interview.

"It's all coming together. We no longer have this treatment-versus-prevention conversation. The question now is about making the best of the resources we have, and in the most intelligent way."

Many terrible problems remain, Hirnschall cautioned.

More than 33 million people live with the virus and each year 2.7 million more cases of HIV occur. Stigma, ignorance and discrimination, in many places, are entrenched. Millions of poor, needy people have yet to clutch the drug lifeline.

To help them, a key question in Vienna is how to finetune the use of antiretrovirals and mesh them with low-cost medical support, using nurses or medical orderlies as substitutes for doctors.

Doctors may be advised to start prescribing anti-HIV drugs at an earlier stage of infection, a tactic that would save more lives and, say some, be a cost-saver too, as healthy people are more productive for longer.

Yet does the world have the will, at a time of belt-tightening, to foot the bill for treating people sooner?

This year, 25 billion dollars has to be mustered for fighting AIDS in poorer countries, according to a UNAIDS estimate. So far, there is a funding shortfall of 11.3 billion, according to an analysis published last week in the US journal Science.

That means a 2006 vow by UN members to provide "universal access" to HIV drugs, prevention, treatment and care by the end of 2010 is set to become one more headline-making political promise that fell flat.

"The success of ARVs (antiretrovirals) made it so people think HIV is no longer there," said Julio Montaner, director of the BC Centre for Excellence in HIV/AIDS in Vancouver, Canada, and president of the International AIDS Society, which is organising the conference.

"Politicians basically react on a short-term agenda. Since HIV treatment became effective, people are not under the same pressure that they used to be."

The Vienna conference will also turn the spotlight on Eastern Europe, where the epidemic is being driven especially by intravenous drug users.

Russia and Ukraine, the two hotspots of infection, are under pressure to scrap policies that criminalise drug users and to encourage needle-exchange programmes and help to wean addicts off heroin by using methadone, a safer substitute for opiates.

Jul 15
Port workers first to fall ill
The Mumbai Port Trust (MbPT) workers, most of whom reside at the nearby Haji Bunder, were the first to feel the effects of the chlorine leak. Minutes after the gas leak in the early on Wednesday, thousands of residents began to complain of burning eyes and chest congestion.

Of the 120 victims who were hospitalised, 62 were MbPT workers.

"The incident occurred around 3 am when most people were asleep. This added to the confusion as misinformation began to pour in,'' said Rajesh Shinde, who runs a small shop in the area.

Several port workers earn their livelihood by collecting coal that falls off during loading and unloading of ships. These men were the first to bear the brunt of the gas leak. The fumes later spread to the residential areas near Haji Bunder. "Most of those who were hospitalised were discharged by afternoon,'' said Sudhir Kamble, a worker.

Residents had seen the gas cylinders lying unattended for years. Mohammed Shaikh, a taxi driver, said that the dock near Haji Bunder was used several years ago for unloading of chemicals, but later only ships transporting coal started using it.

Though this small group of houses and hutments lies in central Mumbai, it is virtually cut off from the city because of poor roads and surrounding MbPT warehouses. The seclusion was obvious on Wednesday when panic spread that a poisonous gas leak had left scores ill and maybe a few dead in the area. By afternoon, however, the situation was normal and the only visible signs of the chlorine leak were a posse of policemen.

Jul 14
330 swine flu cases across India in past week
The swine flu situation continues to be serious in the four southern states and Maharashtra, which have reported 319 of the 330 H1N1 infections in the last one week, while a boy died of the virus in New Delhi.

Swine flu has [photo gallery] claimed 17 lives across the country since July 5 and Kerala, Maharashtra, Karnataka, Andhra Pradesh and Tamil Nadu continue to be the worst affected states, according to official figures. According to the health ministry, both Maharashtra and Kerala reported eight deaths each while one was reported from Andhra Pradesh. Kerala had the highest number of 178 confirmed reports of swine flu. Maharashtra follows with 91 cases while Karnataka has 19, Andhra Pradesh 18, and Tamil Nadu 13. The number of infections are, however, lower than the previous week as 370 cases were reported between June 28 and July 5.

The infection was reported from the eastern part of the country for the first time this week with seven cases in West Bengal. The national capital received a jolt with a death being reported due to swine flu. At least seven cases have been reported from New Delhi since June 10. "There have been seven cases since June 10, but all patients have picked up the infection from out of Delhi," a health official said.

One death was reported from Ram Manohar Lohia hospital Friday. "The last case was of the boy from Ghaziabad who died in a Delhi hospital but he had got the infection from out of Delhi," the official said, adding that the government was fully prepared to deal with the H1N1 virus.

Since the outbreak of swine flu in May last year, India has recorded 33,783 cases of the disease so far while a total 1,624 deaths have been reported.

Jul 14
Cancer Awareness and Detection Drive in Meghalaya
The complete population of Meghalaya will benefit under the cancer awareness and detection drive which will be conducted by the first mobile cancer detection unit in India and the whole project will be completed by March 2013.

The U.K.-based MKC Roko Cancer Trust in partnership with the Government of Meghalya is undertaking this project, said Dr.Puneet Gupta, Senior Medical Advisor, Apollo Cancer Institute.

Meghalaya is the first Indian State to launch a cancer screening campaign for the entire state, he added

Around one lakh people will be provided free awareness about cancer and free detection camps would be orgnised at remote villages to initiate a drive to fight breast, cervix and oral cancer. In all, seven districts of Meghalya will be covered by December 2010.

The screening campaign was launched on April 15, 2010 at the Civil Hospital, Shillong

Dr.Gupta said two state-of-the-art mobile cancer detection units worth Rs 2 crore have been provided by the MKC Roko Cancer Trust to Meghalaya Government. These units have been stationed at Shillong and Tura, and would travel to various places whenever free cancer awareness and detection camps are conducted.

The first unit would cover the Khasi region and the second unit would cover the Garo region.

A team of doctors and volunteers will travel with the unit providing free detection facilities and further investigation test to the people at their doorstep. . This facility would be provided free of cost.

The MKC Roko Cancer Trust has covered eight Indian states so far, including Punjab, Delhi, Uttar Pradesh, Andhra Pradesh, Madhya Pradesh, Maharashtra, Karnataka and Goa.

Jul 13
Good news for diabetics: No more daily jabs
Diabetics of the world, rejoice.

That daily shot of insulin may soon be a thing of the past.

Scientists at the National Immunology Institute, New Delhi, led by its director Dr Avadhesha Surolia, have developed a new form of insulin which can could maintain normal blood sugar levels for over 120 days.

The insulin currently available can do this for a maximum of 18 hours, forcing diabetics to take at least one injection daily to sustain their sugar levels. With this new product, they can now restrict their shots to once every four months.

Dr Surolia said the new product was based on the principles of 'protein folding', and could release insulin molecules in a controlled and sustained manner for over 120 days.

"The just above basal level of human insulin released in a sustained manner has been found to be effective in not only controlling the upsurge in the level of blood glucose after meals, but also in preventing the dreaded early morning hypoglycaemia, which is caused by low glucose levels," he was quoted as saying.

The team has already patented the technology and transferred it to a US-based company for fine-tuning and clinical trials, and the product is likely to be in the market in about six years.

"It is a multi-million dollar technology transfer agreement with royalties once the product goes to the market and if I am not wrong it is one of the biggest scientific innovations to have come from a government-owned research laboratory," Dr Surolia said.

Once it arrives, the technology has a ready-made market in the country of its birth.

India is known as the diabetes capital of the world, with an estimated 50 million diabetics in the country.

Jul 13
A DIABETES BREAKTHROUGH FROM INDIA
A team of Indian scientists has discovered a novel form of insulin that could drastically reduce the suffering diabetics face in controlling their blood sugar.

For the diabetics, daily painful pinpricks to inject doses of insulin is a routine affair, now in a new discovery scientists claim a single shot of insulin could help keep sugar levels under control for more than a month. Today the effect of each insulin injection lasts at best for a day.

India is considered the diabetes capital of the world, with as many as 50 million people suffering from this chronic disease, so any new discovery is welcomed with open arms.

The team spent 2 million rupees and took two years to come with this novel solution. These scientists have already patented the technology, commercialized it and the new insulin could well become a big money spinner in times to come, feels the man who discovered this new form of insulin.

"It is a multi-million dollar technology transfer agreement with royalties once the product goes to the market and if I am not wrong it is one of the biggest scientific innovations to have come from a government owned research laboratory," said Professor Avadhesha Surolia, Director, National Immunology Institute, New Delhi.

The researchers treated natural human insulin at varying temperatures and chemical conditions and one such special formulation does the magic. In experiments done on rats, mice and rabbits the team could control the sugar levels like of these diabetic rats simply by giving an injection once every three months.

Imagine having to do away with multiple injections everyday to control the sugar problem. The simplicity of the discovery and its huge potential has attracted immediate attention.

"Both conceptually and for clinical practice it is an exciting discovery because it uses natural chemically unchanged insulin and clinically it is useful because it provides ease for patients by reducing the number of pin pricks," said Dr Ambrish Mithal, Diabetologist and president, Endocrine Society of India.

It is not often that new drug is discovered in India, but its use in humans could still be many years away.

The new insulin molecule discovered by Indians in India could become a blockbuster drug in times to come as it holds a lot of promise, currently being tested on animals like on rats, it will soon undergo human trials and then it may become available as drug for the treatment of diabetes.

Jul 13
STUDY SHOWS HEALTHY PEOPLE HIT HARD BY H1N1 FLU
More than half of people who died from swine flu or were admitted to hospital with it during the first wave of the H1N1 pandemic in Britain were previously healthy people with no underlying risks, a study has found.

The research findings support many health authorities' policies to prioritise pregnant women, children under the age of 5 and those with long term respiratory problems such as asthma for vaccination against the H1N1 virus known as swine flu.

But they also suggest that everyone with asthma might benefit from vaccination, not just those with severe disease, researchers from the University of Nottingham said.

"Our findings support the use of H1N1 pandemic vaccine in pregnant women, children aged under five years and those with chronic lung disease as a priority, including patients with asthma, regardless of severity," they wrote.

The findings, published on Tuesday in the journal Thorax, a British Medical Journal title, were based on an analysis of clinical data from 55 hospitals in 20 towns and cities in the first wave of the H1N1 pandemic during May to September 2009.

Between late April and late September 2009, data were collected on 631 people with swine flu -- 405 of them adults.

Their ages ranged from 3 months to 90 years. Around 36 percent were under 16 and one in 20 (5 percent) were aged 65 and older and 27 patients, or 4 percent, were pregnant.

This indicates that pregnant women were around three times as likely to require hospital admission once infected with swine flu as women who were not pregnant, the researchers said.

The World Health Organisation (WHO) said last month that the H1N1 pandemic is not yet over, although its most intense activity has passed in many parts of the world.

Britain was one of the first European countries hit by H1N1, which emerged in Mexico in March 2009 and was declared a pandemic by the WHO in June 2009.

Drug companies such as GlaxoSmithKline, Novartis, Sanofi-Aventis and Baxter, among others, developed H1N1 vaccines and governments ordered millions of doses for immunisation campaigns to slow the virus' spread.

As in other countries, health authorities set priorities for pregnant women, the sick and the young to be first in line for vaccines, particularly those with lung conditions such as asthma.

The Thorax study found that 55 percent of all hospital admissions and 59 percent of H1N1 deaths in hospital occurred in people with no previous health problems. Just under half of patients had underlying conditions, mostly asthma.

WHO experts have said the H1N1 virus, which has so far claimed at least 18,000 lives worldwide, remains a threat to some vulnerable people, notably pregnant women, young children and those with respiratory problems, and such groups would continue to need vaccinations.

Jul 12
Can Homeopathy cure Swine Flu?
The Central Council for Research in Homoeopathy has claimed that Homeopathy can cure Swine Flu. Arsenicum album has been suggested as a preventive medicine against Swine Flu.

The suggestion was made at a meeting of department of AYUSH (Ayur Department of Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homoeopathy.

The Homeopathic experts believe that Arsenicum album could be used against all types of flu, including Swine Flu.

The Arsenicum album 30 pills - four pills for adults and two pills for children need to be taken for three days on empty stomach to prevent Swine Flu and other flu-like illness.

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