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Nov 14
Too much selenium linked to high levels of cholesterol
High dietary intake of selenium may increase risk of high cholesterol, a new study by Dr. Dsverio Stranges at the University's Warwick Medical School suggests.

The study recently published in the Journal of Nutrition found that in people who had higher levels of serum selenium, the total cholesterol level increased by 8 percent compared to those who had lower levels.

Selenium is a trace essential mineral and consumers use it as a dietary antioxidant supplement
. Selenium is high in Brazil nuts produced from selenium-rich soil, shrimp, carb meat, salon, halibut, brown rice, and whole wheat bread.

Dr. Stranges and colleagues examined data from 1042 participants aged 19 to 64 in the 2000-2001 UK National Diet and Nutrition Survey. The subjects were interviewed for their eating and drinking habits. Blood samples were taken for analysis.

Higher selenium levels were not just linked with higher total cholesterol.

The researchers also found that higher levels of selenium in the blood also raise non-high density lipoprotein by 10 percent. Lipoprotein can help predict the risk of a heart attack or chest pain.

Additionally, they found that of those with the highest selenium levels, 48.2 percent reported that they regularly took dietary supplements.

It is uncertain whether higher levels of serum selenium are the cause for the increase in total cholesterol and non-HDL cholesterol. The dyufy merely found the association between high selenium levels and higher levels of cholesterol.

Nov 11
Yoga Linked To Healthy Heart
Researchers in India who compared the heart rate variability of men who practised yoga regularly and men who did not, concluded that practising yoga was associated with a healthier heart because the heart rate variability of the yoga practitioners showed evidence of stronger control by the parasympathetic (vagal) nervous system.

The study was the work of Ramesh Kumar Sunkaria, Vinod Kumar, and Suresh Chandra Saxena of the Electrical Engineering Department, at the Indian Institute of Technology in Roorkee, in Uttrakhand, and is to be published in a forthcoming 2010 issue of the International Journal of Medical Engineering and Informatics.

Heart rate variability is a measure of the beat-to-beat changes in heart rate. In healthy people it is high, whereas people with cardiac abnormalities generally have low HRV.

The autonomic nervous system regulates heart rate via two routes: the sympathetic and parasympathetic nervous systems.

The sympathetic nervous system causes HRV to go up, while the parasympathetic depresses it. When working well together, the two ensure that the heart rate is steady but ready to respond to changes caused by eating, the fight or flight response, or arousal, the researchers told the press.

Earlier research suggests that HRV is also a marker of dynamic and cumulative load. As a measure of dynamic load, it responds to stress, such as when we are under pressure to make a complex decision quickly, our HRV drops.

As a marker of cumulative load, it declines with age, in contrast to heart rate which rarely changes signficantly with age. Research suggests that regular physical activity (which also slows down the aging process), raises HRV, presumably by improving parasympathetic control which raises "vagal tone".

Many yoga practitioners believe yoga improves health through regular practice that focuses on breathing, stretching, postures, relaxation and meditation.

For the study, the researchers analyzed the HRV spectra of the electrocardiograms (ECGs) of 42 healthy male yoga practitioners and 42 healthy male non-practitioners aged from 18 to 48 years. All participants were volunteers.

The researchers said that HRV spectral analysis is an important way of exploring heart health and how the heart is regulated. By looking at different frequency bands of HRV in short term episodes, it is possible to see for example how well the heart responds to changes in the body controlled by the sympathetic and the parasympathetic nervous systems.

For example, very low frequency (VLF) variations are linked to temperature control changes. while low frequency peaks are linked to sympathetic control and high frequency peaks with parasympathetic control, explained the researchers.

Nov 11
Doctors strike claims a dozen lives: Bihar
Nearly a dozen patients who were admitted to the Patna Medical College and Hospital (PMCH) here died because of a strike by junior doctors which entered its second day Wednesday, officials said. The doctors are demanding payment of the increased stipend that was promised to them earlier.

"All the patients died during the first 24 hours of the ongoing strike," an official said. More than 500 junior doctors went on an indefinite strike late Monday night, demanding payment of the increased stipend they were promised after a round of agitations this August.

The strike has badly hit the emergency services and dozens of surgeries have been postponed. Hospital authorities have sought the help of the health department to cope with the situation and have asked for 100 doctors from various parts of the state.

"Junior doctors were forced to go on strike as the government was not sticking to its promise," Naqui Imam, a leader of the junior doctors' association, told IANS. "The Bihar government has failed to pay us the increased stipend it promised."

"In August after an assurance from the Bihar government of a hike in stipend, we withdrew our five-day-long strike. But we were not paid," a doctor said.

Hundreds of poor patients, who came for treatment from across the state, have been victims of the ongoing strike. The state government has asked the hospital authorities to hold a meeting with the junior doctors and persuade them to end their strike.

Nov 10
Obesity can cause cancers, says study
Over 100,000 types of cancers are caused by obesity, according to an American study.

Excess body fat makes a person vulnerable to cancer by increasing the amount of hormones like estrogen circulating in the body and disrupting how the body processes insulin, which is linked to higher risk of cancer. It also triggers low-grade inflammation in the body, which is increasingly being found to play a role in cancer.

Researchers from American Institute for Cancer Research suggest that people should maintain a normal body weight and remain physically active throughout life. Weight gain after a cancer diagnosis is also likely to affect the outcome, say researchers.

"An increasing number of studies suggest that regular physical activity improves cancer survival, even among survivors who are overweight or obese," the Independent quoted AICR researchers as saying.

"Public awareness of the link between obesity and cancer risk is alarmingly low," said Alice Bender, MS, RD, Nutrition Communications Manager at AICR. We are working towards a day when obesity is right up there with tobacco in the public eye," Bender added.

The AICR estimates show that excess body fat is linked to 49 per cent of endometrial cancers , 35 per cent of esophageal cancers 28 per cent of pancreatic cancers, 24 per cent of kidney cancers, 21 per cent of gallbladder cancers, 17 per cent of breast cancers and 9 per cent of colorectal cancers.

Nov 10
India's swine flu toll touches 502
Seventeen swine flu deaths, 15 of them from Rajasthan, were reported on Monday, taking the country's toll to 502, health department officials said here.

While one death was reported Monday in Rajasthan, the rest 14 had occurred in the state earlier.

With these 15 deaths, the toll has jumped to 17 in Rajasthan where 101 people have been tested positive for the contagious flu so far.

'State health authorities of Rajasthan have communicated 14 deaths of laboratory confirmed cases from the various districts of Rajasthan,' said an official here.

While six deaths occurred in Jaipur, five were reported from Jodhpur and three from Kota. These deaths had occurred between Oct 7 to Nov 7, the health ministry official said.

One death each was reported from Kerala and Orissa Monday. In Kerala, 21 people have succumbed to the virus, while for the first time one death was reported from Orissa, authorities said.

Also, 95 new cases were reported in the country, taking the total number of people affected with the flu to 14,572.

'Till date, samples from 76,450 people have been tested for Influenza A (H1N1) in government laboratories and a few private laboratories across the country, and 14,572 of them have been found positive,' said a statement issued here.

Delhi recorded 19 new cases Monday. With this, the number of people affected with the flu has gone up to 3,623 - the second highest in the country. As many as 16 people have died due to the influenza in the national capital.

Maharashtra continues to report new cases. On Monday, 11 people were tested positive for the flu. With these, 3,727 people have been detected with the flu. As many as 207 people have died in the state.

New cases were also recorded from Tamil Nadu (16), Karnataka (three), Haryana (four) and Andhra Pradesh (one).

Nov 09
Circumcision Can Reduce AIDS Risk, Study
Circumcision does not decrease a man's sexual pleasure or function, but it does help reduce his risk of contracting the AIDS virus and suffering a penile injury, according to two new studies.

Austrian researchers analyzing biopsies from 20 circumcised and uncircumcised men found that the inner foreskin of the penis contains a higher concentration of Langerhans cells -- a prime target of the human immunodeficiency virus, or HIV -- than any other part of the male foreskin. Because this would make the inner foreskin more susceptible to HIV, removing it through circumcision would help lower a man's risk of contracting HIV, they concluded.

In the second study, a two-year study of nearly 3,000 Kenyan men found that those who were recently circumcised were less likely to suffer coital injuries, such as scratches, cuts, scrapes or soreness, than those who had their foreskin intact. Sexual function was determined to be similar between the circumcised and uncircumcised groups, according to the research team, which was from the United States, Canada and Africa.

The studies are to be presented this week in Chicago at the annual scientific meeting of the American Urological Association.

"These are important reports which support the concepts that circumcision does not interfere with sexual function and that circumcision is an important element of HIV prevention in sub-Saharan Africa," association spokesman Dr. Ira D. Sharlip said in a news release issued by the organization.

"At the same time, it should be emphasized that circumcision must be combined with other techniques of HIV prevention, such as safe sex and voluntary testing," he said. "It is not sufficient to rely on circumcision alone to prevent HIV transmission."

Nov 09
Exercise Cuts Prostate Cancer Risk
A new study suggests that men who get moderate amounts of exercise regularly may reduce their risk of prostate cancer, including the type consisting of aggressive, fast-growing tumors.

The study, published in the November 2009 issue of Journal of Urology, showed prostate cancer was less likely to be diagnosed in men who got exercise regularly than those who led a sedentary lifestyle.

Dr. Stephen J. Freedland and a team of his colleagues of the Duke University Prostate Center and the VA Medical Center in Durham, North Carolina analyzed data from 190 men who underwent biopsies for suspected prostate cancer and found the association.

They found that those patients who exercised moderately, or those who engaged in three to six hours of walking each week, were two-thirds less likely to be diagnosed with prostate cancer than their sedentary counterparts.

Of 111 men who followed a sedentary lifestyle in the study, about 50 percent were diagnosed with the disease compared to 27 percent of those who exercised to a degree equivalent to three to six hours of walking each week.

The researchers also found that men who got the amount of exercise equivalent to one to three hours of walking each week were 86 percent less likely to develop an aggressive form of the cancer.

Of the men diagnosed with prostate cancer, aggressive cancer was found in 51 percent of those who lived a sedentary life and only 22 percent in those who were physically active - getting the equivalent of one to three hours of walking every week.

The study found an association between exercise and reduced risk of prostate cancer. But the results do not prove that exercise is the cause for the reduction in the male reproductive cancer; however, the possibility cannot be excluded either.

Exercise or being physically active has been linked to a reduced risk of cancer in general, not just prostate cancer. One possibility is that those who exercise may follow a healthy lifestyle including a healthy diet.

However, exercise by itself may potentially have a protective effect against prostate cancer and possibly other types of cancer as well.

To say the least, it has been known that exercise lowers blood levels of sexual hormones like testosterone and others that are known to promote prostate cancer growth. Exercise can also boost immunity and the body's anti-oxidation mechanisms, which may help reduce odds for men to acquire prostate cancer.

A recent study published on Oct 27, 2009 in the online British Journal of Cancer, also suggests that being physically active may help reduce risk of prostate cancer.

The study, led by N. Orsini from Karolinska Institutet in Stockholm, Sweden and colleagues found an inverse association between physical activity, such as walking or bicycling, and reduced risk of prostate cancer.

Orsini and colleagues analyzed data from a cohort of 45,887 men aged 45 - 79 years; the researchers followed them between January 1998 and December 2007, checking for prostate cancer incidence. They also tested the patients between 1998 and December 2006 for its subtypes and for fatal prostate cancer.

During the follow-ups, 2735 cases of prostate cancer and 190 cases of fatal prostate cancer were recorded.

The researchers observed prostate cancer incidence in the top quartile of lifetime total physical activity was decreased by 16%, compared with that in the bottom quartile. A similar inverse association was also found between average lifetime work or occupational activity and walking or bicycling duration and the risk of prostate cancer.

Compared with those who were required to sit for the most of their workday, men who sit only half of the time experienced a 20% reduced risk.

For every 30 minutes per day increment of lifetime walking or bicycling in the range of 30 to 120 minutes per day, the risk for total prostate cancer decreased by 7 percent; for localized prostate cancer by 8 percent and for advanced prostate cancer by 12 percent.

An estimated 192,280 men in the United States will be diagnosed with prostate cancer in 2009. The disease is expected to kill 27,360 men in the country this year, according to the National Cancer Institute.

Nov 09
'Obesity must be avoided in pregnant women'
Obesity in pregnant women is fast emerging as major threat for successful deliveries and the changing life style is likely to compound
the problem in future, says Dr Reena Srivastava of BRD Medical College, Gorakhpur, while delivering Dr Meena Mukherji oration on the concluding day of the three-day 21st annual conference of UP chapter of Federation of Obstetrics and Gynaecological Society of India (FOGSI) in Banaras Hindu University on Sunday.

"Traditionally, the Indian women carry excess total body fat (truncal obesity) and more cases of abdominal obesity are pouring from urban areas and metropolitan cities, she said on the occasion. A high percentage of urban as well as rural women have greater body mass index (BMI) and it makes the antenatal and delivery services even more difficult," she added.

"Ideally, the waist to hip ratio should not be more than 0.9 in pregnant women, but high number of overweight and obese pregnant women, especially from the urban areas, are coming to us, enough to raise concern," she said. "It is mostly related to wrong choice of food and improper diet during pregnancy. Similarly, sedentary life style and restricted activities also aggravate the problems during pregnancy," she added, while referring to recent studies and surveys on Indian pregnant women.

Stressing that a number of risk factors including diabetes, hypertension, cardio-vascular diseases, respiratory problems and haemorrhage were associated with obese women, she also emphasised that complications such as more blood loss and prolonged labour pain pose challenge to gynaecologists.

Nov 07
The 'Energy Gap' Addresses Obesity
The November issue of the Journal of the American Dietetic Association features a commentary by James O. Hill, an honorary ADA member, professor of pediatrics and medicine and director of the Center for Human Nutrition at the University of Colorado-Denver. He is also co-founder of America on the Move, a national weight gain prevention initiative that aims to inspire Americans to make small changes in how much they eat and how much they move to prevent weight gain.

This special commentary, providing health-care professionals with insights into obesity and ways to effectively treat and prevent it, is available to subscribers and non-subscribers of the Journal.

The term "energy gap" was developed to estimate the degree of change in the energy balance point required for success in achieving weight loss, gain or management. The energy gap concept is especially relevant when addressing prevention of excessive weight gain and maintenance of weight loss.

"With the exception of bariatric surgery, there has not been a great deal of success in helping people maintain substantial weight losses," Hill writes. "Many people can achieve significant weight losses with our current interventions, but very little of this weight loss seems be maintained by most people over the long term. The energy gap can help estimate the degree of behavior change that must be maintained to maintain a given amount of weight loss for any individual."

The commentary also points out the effectiveness of small behavior changes in preventing further weight gain in those who are already overweight or obese or preventing people from becoming overweight or obese. Evidence suggests that small changes, such as eating 100 less calories per day, are easy to achieve and sustain for most people.

"[While] restoring normal body weights among those already obese would likely require more dramatic intervention, including pharmacological and surgical treatment," Hill writes, "a small-changes approach must be included in public health strategies and public policies to address obesity."

Nov 07
Cancer Crusade
India's most frightening epidemic, which isn't just robbing people of their lives but also their families of livelihood - is expected to get worse over the next decade, especially for women.

According to the Indian Council of Medical Research's (ICMR) projection in a landmark Trends in Cancer report, yet to be made public, the country will see a 21 per cent overall increase - over 1.06 lakh additional cases of cancer every year in women by 2020, as against 79,000 new cases of cancer in men during the same period.

This landmark analysis, based on the pattern of cancer incidence between 1982-2005 (24 years) in India, has made some startling revelations. Cases of leukaemia or blood cancer will increase by almost 77 per cent in women by 2020, followed by cancer of the colon (69 per cent) and liver (61 per cent). However, in sheer numbers, the main culprit in the next 10 years will be breast cancer.

While India is expected to see a 41 per cent increase in breast cancer cases by 2020, in numbers it would mean almost 36,000 additional women falling victim to it. In comparison, cervical cancer, which has been Indian women's real curse will show a dip in actual number of cases. Cancer in other common body sites - uterus, ovary, gall bladder and stomach will see a 21 per cent increase. According to Dr Vinod Raina, head of medical oncology at the All India Institute of Medical Sciences (AIIMS), though leukaemia may see the maximum increase in incidence rates, in sheer numbers it is still uncommon. Breast cancer, on the other hand, will form the lion's share of new cancer cases in the next 10 years, which will be primarily due to India's ageing population.

Says Dr Raina, "Cancer is age-related . So, the longer women live, the more will be their chances of suffering from cancer." He goes on to add, "Colon cancer cases will increase due to a change in Indian dietary habits. High meat intake is known to cause colon cancer. That's why vegetarians usually don't suffer from it. The main culprits behind liver cancer, however, are Hepatitis B and C infections."

According to Dr Shyam Aggarwal, medical oncologist at Sir Ganga Ram Hospital, late marriages, delayed child bearing and giving birth to lesser number of children, besides ageing are leading to an increased risk of breast cancer. "Almost 70 per cent of these cases are dependent on the female hormone - oestrogen . Giving birth breaks the hormonal cycle that reduces the chances of breast cancer. The sooner a woman breaks the cycle of oestrogen formation with early pregnancy, the greater the chances of a reduction of cancer cells, which multiply under the influence of oestrogen."

Increased obesity too is a major risk factor. In India, nearly 6 crore women are believed to be overweight and studies have shown that about one out of 12 new cases of cancer is because of excess weight. Adds Dr Aggarwal, "Fat cells also produce oestrogen. A diet full of fat is also not helping matters." According to an elite international panel that analysed over 7,000 studies in the last 40 years, over 40 per cent of all cancers are a direct result of our diet, body structure and exercise habits.

The panel in its 521-page report - Food, Nutrition, Physical Activity and the Prevention of Cancer - prepared after five years of analysis , made crucial recommendations that people across the globe must follow to minimise their chances of getting cancer. However, Indians fared badly with regard to most of the recommendations . Studies revealed they consume just 130 gm of fruits and vegetables a day as against the recommended amount of 400 gm. While salt consumption shouldn't be more than 6 gm a day, Indians consume anywhere between 10-15 gm.

Consumption of red meat was found to have a direct link with cancer - with over 64 per cent of non-vegetarians in India consuming more than the recommended amount of under 500 gm a week. The same is the case with the consumption of soft drinks and fast food as well. Then, while more than 30 ml of alcohol a day is dangerous, binge drinking is on the rise here.

New mothers should ideally breastfeed their children for six months, but Indian mothers do so for just about two months, on average. So, only 51 per cent of the infants are breastfed for the first six months.

Treat these statistics as a wake-up call and start making small changes to your lifestyle to keep cancer at bay.

Cancer, a generic term for a group of more than 200 diseases that are expected to kill 84 million people between 2005 and 2015, 70% of whom will be in low and middle income countries

At any given time, there are 25 lakh cancer patients in India

It is the third biggest killer in the country, claiming 4 lakh lives every year

About 7-9 lakh new cancer cases are detected in India annually

Every hour, cancer kills at least 50 people in India, and 100 new cases are detected

Early detection is vital to fight cancer, especially of the breast, cervix, mouth, larynx, colon, rectum and skin

At present, in India, over 70% cases are detected at the terminal stage

The current oncologist-patient ratio is 0.98: 1 lakh cases

With regular screening, mosts cancers can be prevented

Source: Ministry of Health and Family Welfare

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