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Oct 04

Ageing Process Can Be Reversed by stem cells

Posted on Monday, 4th October 2010

NEW RESEARCH IN MICE SHOWS AGEING CAN BE REVERSED BY STEM CELLS;
by mixing blood of old people with the blood of young people, these
young bllod cells rejuvenate old blood cells. This has been demonstrated by THE HAVARD STEM CELL INSTITUTE by a recent published study on Mice. When blood from young mice bone marrow injected in old mice, these blood cells after entering into Bone Marow of Old mice revitalise these Blod Stem Cells present in Bone Marrow. Reseacher concluded that usually in old Mice Bone marrow produce that type of Blood stem cells which generate more Myeloid series blood cells which control infection or tumors but less amount of Blood stem cells whch produce Lymphoid series cells that orchestrate or regenerate tissue Repair as seen in young Mice but after the injectionof young blood cells even old Mice started producing stem cells that is doing tissue
repair. The study is yet to be done in Human being.

Refered by: DR. D. R. Nakipuria

http://indiaheartbeat.com/doctor/profile.php?profile=MzIxODk=

Oct 01

2.6 Lakh HIV patients have no access to treatment

Posted on Friday, 1st October 2010

Around 3.2 lakh HIV patients in India were on life-saving anti-retroviral therapy (ART) in December 2009 - more than 85,000 patients from the previous year. Be that as it may, 2.6 lakh people are still in dire need of ART. According to the World Health Organisation's (WHO) latest report, "Towards Universal Access", which tracks progress in achieving the 2010 target for HIV prevention, treatment and care; around 5.8 lakh HIV patients required ART in end-2009.
Globally, the HIV epidemic continued to be a real public health challenge as around 33.4 million people are suffering from the lethal disease. In 2008 alone, 2.7 million people were newly infected with the virus. According to the report, only one-third of HIV patients have been put on ART, and coverage of prevention interventions is largely inadequate. This year, WHO's revised guidelines on ART for adults and adolescents, including would-be mothers, said ART would be initiated when CD4 cell counts reach or drop below 350 cells/mm3, irrespective of whether the patients have clinical symptoms. As per this count, though an estimated 11 -14 lakh HIV patients in India need ART, only 23% are receiving the treatment.
The number of pregnant women, who require ART, is pegged at 43,000. But only 21% are covered. Another 30,000-76,000 HIV positive children, too, require ART. However, there has been a spurt in the number of HIV tests across the world. For instance, 100 countries had tested 67 mn people last year. In 82 countries - for which comparable data was available for 2008 and 2009 - the median number of tests performed per 1,000 people had increased from 41 to 50, respectively. ART coverage, among young adults less than 15 years, has gone up from 22% in 2008 to 28% in 2009.
Even the percentage of HIV positive pregnant women receiving ART to prevent mother-to-child transmission has increased from 45% in 2008 to 53% in 2009. . In end-2009, 5.25 mn people were receiving ART in low and middle-income countries, including India, which translates to an increase of over 1.2 mn people from the previous year. The report maintains that HIV-related TB remains a cause for concern. In 2008, of the 9.4 mn TB cases reported worldwide, an estimated 1.4 million were diagnosed among HIV patients. Though the rate of HIV test and counselling for TB patients is rising, the initiative is insufficient.

Oct 01

Garlic oil can prevent diabetic heart dysfunction--study

Posted on Friday, 1st October 2010

Garlic oil can protect against diabetic cardiomyopathy, a form of heart disease in people with diabetes, reveals a novel study.

Garlic has an enormous potential to prevent cardiomyopathy, which is a leading cause of death amongst diabetics.

It works by controlling the abnormally high sugar levels that occur during diabetes on a common basis.

The study, conducted by researchers from Taiwan, took the help of a few diabetic laboratory rats for the research.

The rats were fed either garlic oil or corn oil by the researchers. They were then observed to see which oil led to better prevention of cardiomyopathy.

Results of the study
The rats that were given garlic oil experienced beneficial changes associated with protection against heart damage, the study revealed.

Diabetic rats showed significantly decreased levels of myosin heavy chains, key contractile proteins in the heart, which were dose dependently attenuated by garlic oil.

The garlic oil rich diet had reduced the cardiovascular complications in the rats that had consumed it compared to the ones who had been given corn oil.

Garlic oil rich diet was also reported to reverse the effects of diabetes on cardiac [pertaining to the heart.] output and the heart's pumping capacity in a dose dependent manner.

Overall, diabetes related cardiac dysfunctions in the rats were dose-dependently relieved with garlic oil.

The changes found in the rats were related to the antioxidant properties of the oil, the researchers found.

20 contributing substances found in oil
On analysis, almost 20 substances that may contribute to this protective effect were found in garlic oil.

"Our results show that garlic oil supplementation for diabetic rats leads to several alterations at multiple levels in hearts including cardiac contractile functions and structures, myosin chain gene expressions, oxidative stress, and apoptosis and related signaling activities," wrote the researchers, led by Wei-Wen Kuo from the China Medical University in Taiwan.

"In conclusion, garlic oil possesses significant potential for protecting hearts from diabetes-induced cardiomyopathy," the study authors said in a statement.

In addition, garlic (Allium sativum) has been found to exhibit several health benefits, including inhibiting enzymes involved in lipid synthesis, decreasing platelet aggregation, preventing lipid peroxidation, and increasing antioxidant status.

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