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Mar 04
Pot can be detected in blood of daily smokers for a month after last intake
For the first time, a new study has found that cannabinoids-psychoactive compounds of marijuana-can be detected in the blood of daily pot smokers during a month of sustained abstinence.

Researchers behind the study suggest that the finding can provide real help in the public safety need for a drugged driving policy that reduces the number of drugged driving accidents on the road.

Cannabis is second only to alcohol for causing impaired driving and motor vehicle accidents. In 2009, 12.8 percent of young adults reported driving under the influence of illicit drugs and in the 2007 National Roadside Survey, more drivers tested positive for drugs than for alcohol.

These cannabis smokers had a 10-fold increase in car crash injury compared with infrequent or nonusers after adjustment for blood alcohol concentration.

In this study, 30 male chronic daily cannabis smokers resided on a secure research unit for up to 33 days, with daily blood collection. Twenty-seven of 30 participants were THC-positive on admission, with a median (range) concentration of 1.4 micro g/L (0.3-6.3). THC decreased gradually with only 1 of 11 participants negative at 26 days; 2 of 5 remained THC-positive (0.3 micro g/L) for 30 days.

These results showed, for the first time, that cannabis could be detected in blood of chronic daily cannabis smokers for a month after last intake.

This is consistent with the time course of persisting neurocognitive impairment reported in recent studies and suggests that establishment of `per se` THC legislation might achieve a reduction in motor vehicle injuries and deaths.

This same type of `per se` alcohol legislation improved prosecution of drunk drivers and dramatically reduced alcohol-related deaths.

"These data have never been obtained previously due to the cost and difficulty of studying chronic daily cannabis smoking over an extended period," said Dr. Marylin Huestis of the National Institutes of Health and author on the paper.
"These data add critical information to the debate about the toxicity of chronic daily cannabis smoking," Dr. Huestis added.

The research appeared online in Clinical Chemistry, the journal of AACC.

Mar 04
New tattoo inks may cause complications that mimic skin cancer
Modern tattoo inks are causing increased complications like allergic reactions, serious infections and reactions that can mimic skin cancer, a dermatologist has claimed.

Tattoo ink`s composition has changed dramatically over the years. In the past, metal salts, lead, cobalt and carbon were used in inks but today, many modern tattoo inks (especially intense reds and yellows) contain organic azo dyes with plastic-based pigments, which also have industrial uses in printing, textiles and car paint.

As a result, Michi Shinohara, MD, FAAD, a board-certified dermatologist and clinical assistant professor of dermatology at the University of Washington in Seattle, explained that there are many unknowns about how these inks interact with the skin and within the body and if they are responsible for an increasing number of complications.

One of the most common problems associated with tattooing is allergic reactions to the tattoo pigments. Itching, bumps or rashes can occur days, months or even years after the initial tattoo.

In people suffering with psoriasis and eczema, tattoos may cause the chronic skin conditions to flare.

Sarcoidosis is an autoimmune disorder that is characterized by swelling and itching, which can occur in a tattoo decades after the procedure and can involve other organs, like lungs or eyes.

This type of reaction is not directly caused by the original tattoo, but can show up within the tattoo.

According to Shinohara, Skin cancer can occur within a tattoo, and for that reason tattoo artists need to be careful not to place a tattoo over an existing mole.

However, one reaction that can result is a bump that mimics skin cancer, which can ruin the tattoo.

This type of bump or lesion, which can occur within a tattoo looks like a type of skin cancer known as squamous cell carcinoma.

Since the bump is so hard to distinguish from this skin cancer, it requires a biopsy and, in some cases, may need to be treated as a skin cancer, with additional surgery.

Common infections linked to tattooing include localized bacterial infections.
In addition, there are reports that syphilis and hepatitis B and C are being transmitted due to non-sterile tattooing practices.

However, Shinohara noted that outbreaks can also stem from the tattoo ink rather than the tools used in the procedure.

A recent outbreak of atypical mycobacterial infections has been traced to contaminated tattoo ink, which cause itchy, painful pustules and red bumps within a tattoo during the first month of the procedure.

This type of bacteria is harder to treat than regular staph bacteria and can require a several-month course of oral antibiotics to clear the infection.

Mar 01
Missed meals in childhood linked to pain, depression in adulthood
Children who missed meals can not only have problem concentrating in school, they may also have a higher risk of experiencing pain and depression in adulthood, a new University of Nebraska-Lincoln study has suggested.

Depression and chronic pain are experienced by 44 percent of working-aged adults and the study shows a correlation between childhood conditions and pain and depression in adulthood.

The study by UNL sociologist Bridget Goosby examines how childhood socio-economic disadvantages and maternal depression increase the risk of major depression and chronic pain in working-aged adults.

Goosby examined a survey of 4,339 adults from the National Comorbidity Survey Replication looking for a relationship between circumstances in childhood and physical and mental health in working-age adults. She specifically looked at data from adults 25 to 64 years old.

Goosby said she was surprised to find that experiencing hunger in childhood can lead to chronic pain and depression in adulthood.

"The most robust child socio-economic condition was experiencing hunger. Kids who missed meals have a much higher risk of experiencing pain and depression in adulthood," Goosby said.

The study also found that maternal depression had a correlation with adults having depression later in life.

In the study, Goosby noted that those who grew up with parents with less than 12 years of education had a much higher risk of experiencing chronic pain compared to adults with more highly educated parents, a disparity that becomes evident after age 42 and grew larger over time.

With this information, Goosby said she hopes policymakers will pay attention to creating more healthy family dynamics in society and that the study`s results will give policymakers a reason to examine circumstances in early childhood more closely.

The study is forthcoming in the Journal of Health and Social Behavior.

Mar 01
Modern women 'piling on the pounds due to lack of household chores'
Lack of household work for modern women might be contributing to obesity, a new study has claimed.

According to researchers, since the 1960s, more women have taken desk jobs and cut back on physical activity like household chores.

In 1965, the average women spent nearly 26 hours per week on chores like cooking, cleaning and doing the dishes. Women today allot about half that time for chores, the study revealed.

"What we were trying to find is what has changed in our environment that has led to obesity," study leader Edward Archer, a researcher at the University of South Carolina, told the New York Daily News.

What changed, he said, is that more women went to work at sedentary jobs and fewer engaged in physical activity - like housework.

Obesity rates have been increasing steadily in past decades. In 2004, 32 percent of Americans were obese, compared to 13 percent in the 1960s, according to research from the Johns Hopkins Bloomberg School of Public Health.

For Archer`s study, researchers looked at the time and amount of energy women expended on "household management" over a 45-year span.

Non-working women spent 33.1 hours per week on housework in the 1960s, compared to 16.5 hours in 2010. Working women spent 17.1 hours on housework in the 1960s, compared to 10.4 in 2010.

By 2010, women were devoting 25 percent more time to "screen-based media use" - watching TV or on the computer.

The study is published in the science journal PLOS One.

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